pta — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TJS1779	Protosappanin A	PTA	NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
	Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB inflammation signal pathway; it exerts anti-neuroinflammatory ...
T3263	(6R,7S)-Cefminox sodium heptahydrate	Meicelin,Cefminox Sodium,Alteporina,Tencef	Antibiotic
	(6R,7S)-Cefminox sodium heptahydrate (Meicelin) is a broad-spectrum, bactericidal cephalosporin antibiotic. It is especially effective against Gram-negative and anaerobic bacteria.		Antibiotic
T22520	5-Carboxamidotryptamine maleate	5-CT maleate	5-HT Receptor
	5-Carboxamidotryptamine maleate (5-CT maleate) (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.		5-HT Receptor
T21666	Donitriptan hydrochloride	Donitriptan HCl,Donitriptan monohydrochloride	5-HT Receptor
	Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively		5-HT Receptor
T50092	1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride	1-(7-carbamimidamidoheptyl)guanidine dihydrochloride	Others
	1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerativ...		Others
T37886	1-Heptadecanol		Antibacterial
	1-Heptadecanol is a long-chain primary alcohol with antibacterial activity from Solena amplexicaulis leaves[1]. [1]. Soumendranath Chatterjee, et al. Antibacterial Activity of Long-Chain Primary Alcohols from Solena ampl...		Antibacterial
T34262	RAPTA-C		Apoptosis
	RAPTA-C induces EAC cell cycle arrest and apoptosis via the mitochondrial and p53-JNK pathways, and can be used in the study of breast and ovarian cancer.		Apoptosis
T7998	1,7-Diaminoheptane		Others
	1,7-Diaminoheptane is a compound of the aliphatic amine family. It is used in the synthesis of peptides, peptidomimetics, and other compounds, and has also been used as a substrate in enzyme reactions, as a ligand in met...		Others
T6980	Scriptaid	GCK1026,Scriptide	Apoptosis , Influenza Virus , HDAC , Autophagy
	Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.		Apoptosis , Influenza Virus , HDAC , Autophagy
T9189	Iptacopan hydrochloride	Iptacopan HCl,LNP023 hydrochloride	Complement System
	Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity b...		Complement System
T8273	4,6-Dioxoheptanoic acid	Succinylacetone	Others , Endogenous Metabolite
	4,6-Dioxoheptanoic acid (Succinylacetone) acts as a potent inhibitor of heme biosynthesis.		Others , Endogenous Metabolite
T0201	Meptazinol hydrochloride	Meptazinol HCl	Opioid Receptor
	Meptazinol hydrochloride (Meptazinol HCl) , a unique centrally opioid analgesic, is used as a narcotic antagonist with analgesic properties.		Opioid Receptor
T8666	Naratriptan		5-HT Receptor
	Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.		5-HT Receptor
T6814	Cyproheptadine hydrochloride	Periactin hydrochloride,Anarexol,Cyproheptadine HCl,Nuran	5-HT Receptor
	Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.		5-HT Receptor
T21231	Almotriptan	LAS 31416	5-HT Receptor
	Almotriptan (LAS 31416) is a 5-HT1B/1D-receptor agonist used to treat migraine.Almotriptan is a triptan drug for treatment of migraine headaches.Binding of the drug to the receptor leads to vasoconstriction of the crania...		5-HT Receptor
T2317	Almotriptan Malate	LAS 31416,PNU180638	5-HT Receptor
	Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.		5-HT Receptor
T2S0690	Ecliptasaponin A	Echinocystic acid-3-o-glucoside	Others
	1. Ecliptasaponin A (Echinocystic acid-3-o-glucoside) has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-...		Others
T4054	Dantrolene sodium hemiheptahydrate	Dantrolene sodium hydrate,Dantrolene sodium salt,Dantrium,Sodium dantrolene	Calcium Channel , Autophagy
	Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from t...		Calcium Channel , Autophagy
T6602	Naratriptan hydrochloride	Naratriptan HCl,Amerge,Naramig,GR-85548A hydrochloride	5-HT Receptor
	Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydroc...		5-HT Receptor
T7303	LIXIVAPTAN	VPA-985,WAY-VPA 985	Vasopressin Receptor
	Lixivaptan (VPA-985) is an orally active and selective vasopressin receptor V2 antagonist(Ki = 2.3 nM)		Vasopressin Receptor