Search Result

Search Results for " pem "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T0296	Pempidine	1,2,2,6,6-Pentamethylpiperidine,Perolysen,Pyrilene	Others , AChR
	Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.		Others , AChR
T68126	Pemedolac	Dexpemedolac	COX
	Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.		COX
T1425	Pemirolast potassium	BMY 26517,TWT-8152	Histamine Receptor
	Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium (TWT-8152) exerts its action by blocking the antigen-mediated calcium ion influx i...		Histamine Receptor
T0189L	Pemetrexed disodium	LY-231514,LY231514 disodium,Pemetrexed	Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
	Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has b...
T0396	Pipemidic acid	Acido pipemidico	Antibacterial , Antibiotic
	Pipemidic acid (Acido pipemidico), a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa.		Antibacterial , Antibiotic
TQ0107	Pemafibrate	(R)-K-13675	PPAR
	Pemafibrate ((R)-K-13675) is a highly specific PPARα agonist (EC50: 1 nM).		PPAR
T27322	Fispemifene	HM-101,HM 101,HM101	Others
	Fispemifene (HM-101) is an estrogen receptor modulator (SERM) used to treat genitourinary syndromes and vaginal atrophy.		Others
T6226	Pemetrexed disodium hemipenta hydrate	Pemetrexed Disodium Hydrate,LY-231514 Disodium Hydrate,Pemetrexed sodium hydrate	Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
	Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 6...
T6620	Ospemifene	FC-1271a	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA ap...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T12401	Pemigatinib	INCB054828	FGFR
	Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).		FGFR
T15461	Halopemide		Others , Phospholipase , Dopamine Receptor
	Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2). Halopemid is an antagonist of dopamine receptors. Halopemid can be used in psychotropic research.		Others , Phospholipase , Dopamine Receptor
T0189	Pemetrexed	Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate	DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
	Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).		DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
T9908	Pembrolizumab		PD-1/PD-L1
	Pembrolizumab is a humanized monoclonal antibody inhibiting the PD-1 receptor and the first in the class of agents called the HER2 dimerization inhibitors that impairs the ability of HER2 to bind to other members of the ...		PD-1/PD-L1
T12329	Ospemifene D4	FC-1271a D4	Estrogen/progestogen Receptor
	Ospemifene D4 is a deuterium labeled Ospemifene. Ospemifene is a selective and orally active modulator of estrogen receptor.		Estrogen/progestogen Receptor
T74421	Pemvidutide
	Pemvidutide, a dual GLP-1R/GCGR agonist, significantly lowers body weight, liver fat, and serum lipids, holding promise for non-alcoholic steatohepatitis (NASH) and obesity research [1].
T60950	Pirepemat fumarate
	Pirepemat (IRL752) fumarate can be used in Parkinson's disease study. Pirepemat is a cortical-preferring catecholamine transmission- and cognition-promoting agent [1] [2].
T70583	Pemetrexed Diethyl Ester
	Pemetrexed Diethyl Ester is a protected intermediate in the synthesis of Pemetrexed, a multi-targeted anti-folate that inhibits thymidylate synthase as well as other folate dependent enzymes.
T74111	N-Methyl pemetrexed
	N-Methyl pemetrexed, an impurity found in Pemetrexed, serves as an antifolate cytotoxic agent utilized in cancer research [1].
T25929	Pemetrexed tromethamine	Pemetrexed ditromethamine dihydrate
	Pemetrexed tromethamine is a chemotherapy drug used for pleural mesothelioma and non-small cell lung cancer.
T66032	Pemetrexed disodium heptahydrate
	Pemetrexed disodium is a guanine-derived antineoplastic agent that functions as a nucleic acid synthesis inhibitor through its binding to, and inhibition of, thymidylate synthase.
T10817	Cipemastat	Ro 32-3555	Others
	Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).		Others
T38610	Pirepemat	IRL752
	Pirepemat (IRL752) is a cortical-preferring catecholamine agent that enhances cognition. It is utilized in the investigation of Parkinson's disease.
T78658	Pemvidutide TFA
	Pemvidutide (TFA), a GLP-1R/GCGR dual agonist, effectively reduces body weight, liver fat, and serum lipid levels, and is utilized in research on non-alcoholic steatohepatitis (NASH) and obesity [1].
T69191	Pemaglitazar
	Pemaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist, with hypoglycemic activity.
T60289	Pemirolast
	Pemirolast is an orally active antiallergic agent. Pemirolast attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides, that can be used for bronchial asthma and conjunc...
T40860	Ivospemin
	Ivospemin is an antineoplastic spermine analog.
T69120	Pempidine tartrate
	Pempidine tartrate is a nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more ...
T68992	Pempidine HCl
	Pempidine HCl is a nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more speci...
T77156	Depemokimab
	Depemokimab (GSK-3511294) is a long-acting monoclonal antibody targeting IL-15, utilized in asthma research [1] [2].
T13814	Pemafibrate (racemate)	K13675 (racemate)	Others
	Pemafibrate racemate is the racemate of pemafibrate		Others
T70125	Pemrametostat succinate
	Pemrametostat succinate is an orally active, potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) that potently inhibits tumor growth in vitro and in vivo in animal models.

Compounds

Pempidine

T0296

Synonym: 1,2,2,6,6-Pentamethylpiperidine,Perolysen,Pyrilene

Target: Others, AChR

Pemedolac

T68126

Synonym: Dexpemedolac

Target: COX

Pemirolast potassium

T1425

Synonym: BMY 26517,TWT-8152

Target: Histamine Receptor

Pemetrexed disodium

T0189L

Synonym: LY-231514,LY231514 disodium,Pemetrexed

Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy

Pipemidic acid

T0396

Synonym: Acido pipemidico

Target: Antibacterial, Antibiotic

Synonym: HM-101,HM 101,HM101

Target: Others

Pemetrexed disodium hemipenta hydrate

T6226

Synonym: Pemetrexed Disodium Hydrate,LY-231514 Disodium Hydrate,Pemetrexed sodium hydrate

Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy

Ospemifene

T6620

Synonym: FC-1271a

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Target: Others, Phospholipase, Dopamine Receptor

Pemetrexed

T0189

Synonym: Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate

Target: DHFR, DNA/RNA Synthesis, Antifolate, Autophagy

Target: Estrogen/progestogen Receptor

Pemetrexed Diethyl Ester

T70583

Synonym:

Target:

N-Methyl pemetrexed

T74111

Synonym:

Target:

Pemetrexed tromethamine

T25929

Synonym: Pemetrexed ditromethamine dihydrate

Target:

Pemetrexed disodium heptahydrate

Pemafibrate (racemate)

T13814

Synonym: K13675 (racemate)

Target: Others

Pemrametostat succinate

T70125

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04340	Mucin-1/MUC1 Protein, Human, Recombinant	Human	HEK293
	Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPY-02005	Mucin-1/MUC1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPK-00828	Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)	Human	HEK293
	MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire...
TMPY-06707	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)	Human	HEK293
	Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPJ-00155	Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated	Human	Human Cells
	Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also ...
TMPY-06833	Mucin-1/MUC1 Protein, Human, Recombinant (aa 890-1158, His)	Human	HEK293
	Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPY-06832	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-380, His)	Human	HEK293
	Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPY-02871	Mucin-1/MUC1 Protein, Human, Recombinant (mFc)	Human	HEK293
	Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...