Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 155.00 | |
25 mg | In stock | $ 288.00 | |
50 mg | In stock | $ 450.00 | |
100 mg | In stock | $ 598.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively). |
Targets&IC50 | FGFR4:30 nM, FGFR3:1.2 nM, FGFR1:0.4 nM, FGFR2:0.5 nM |
In vitro | In cells expressing FGFR2-CLIP1 fusion are sensitive to Pemigatinib (INCB054828; IC50 value of 10.16 nM)[3]. |
Synonyms | INCB054828 |
Molecular Weight | 487.5 |
Formula | C24H27F2N5O4 |
CAS No. | 1513857-77-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 40mg/mL (82.05 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Pemigatinib 1513857-77-6 Angiogenesis Tyrosine Kinase/Adaptors FGFR Fibroblast growth factor receptor INCB054828 inhibit cholangiocarcinoma Orally INCB 054828 INCB-054828 Inhibitor antineoplastic inhibitor