orthopoxvirus — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4729	Phosphonoacetic acid		Endogenous Metabolite
	Phosphonoacetate, also known as fosfonet or phosphonacetic acid, belongs to the class of organic compounds known as organic phosphonic acids.Within the cell, phosphonoacetate is primarily located in the cytoplasm. Phosph...		Endogenous Metabolite
T7142	Cephalosporin C zinc salt		Others
	Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 µM), and this inhibition was largely attributable to the presence of zinc.		Others
T0974	Novobiocin Sodium	Albamycinsodium,Cathomycin,Albamycin	Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
	Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T6360	3-deazaneplanocin A HCl		Others , Histone Methyltransferase
	3-deazaneplanocin A (DZNeP)HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM.		Others , Histone Methyltransferase
T0681	Rifampicin	Rifamycin AMP,Rimactane,Rifampin	Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic , Antifection
	Rifampicin (Rifamycin AMP) is an antibacterial drug of the class of rifamycin.
T4971	5'-DEOXYADENOSINE	5′-dAdo	Endogenous Metabolite
	5'-Deoxyadenosine (5′-dAdo) is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long be...		Endogenous Metabolite
T40686	Tiazofurin	NSC 286193,Riboxamide	Dehydrogenase
	Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent IMP dehydrogenase (IMPDH) in...		Dehydrogenase
T7655	Fialuridine	DRG-0098,FIAU	DNA/RNA Synthesis
	Fialuridine (DRG-0098) is a DNA-directed DNA polymerase inhibitor potentially for the treatment of HBV infection with potent activity against hepatitis B virus in vitro and in vivo.		DNA/RNA Synthesis
T6446	Clevudine	L-FMAU,Levovir	HBV , DNA/RNA Synthesis
	Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The ...		HBV , DNA/RNA Synthesis
T4683	Alovudine	3'-Deoxy-3'-fluorothymidine	Antiviral
	Alovudine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and is a better biomarker in pancreatic cancer.		Antiviral
TQ0095	Brincidofovir	CMX001,HDP-CDV	Others , Antiviral , HSV
	Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses.		Others , Antiviral , HSV
T6588	Mitoxantrone	mitozantrone	Topoisomerase , PKC
	Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisome...		Topoisomerase , PKC
T6567	Levofloxacin	Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin	Topoisomerase , Antibacterial , Antibiotic
	Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.		Topoisomerase , Antibacterial , Antibiotic
T1617	Enrofloxacin	BAY-Vp2674,PD160788	DNA/RNA Synthesis , Antibacterial , Antibiotic
	Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.		DNA/RNA Synthesis , Antibacterial , Antibiotic
T6136	Canertinib	PD-183805,CI-1033	EGFR
	Canertinib (CI-1033) is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hyp...		EGFR
T0992	Carbenoxolone disodium	Biogastrone,Duogastrone,Bioral	Gap Junction Protein
	Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ...		Gap Junction Protein
T0902	Ofloxacin	DL8280,Hoe-280,Floxin,Tarivid,Oxaldin	Topoisomerase , Antibacterial , Antibiotic
	Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting i...		Topoisomerase , Antibacterial , Antibiotic
T6244	Cidofovir	HPMPC,GS 0504,(S)-HPMPC	Others , DNA/RNA Synthesis
	Cidofovir ((S)-HPMPC) inhibits virus replication by specific inhibition of viral DNA synthesis.		Others , DNA/RNA Synthesis
T0684	Ribavirin	Tribavirin,ICN-1229,NSC-163039,RTCA	Dehydrogenase , HCV Protease , DNA/RNA Synthesis , Antibiotic , AChR , RSV
	Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
T0863	Idoxuridine	IDU,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid	Antifection , HSV
	Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.		Antifection , HSV