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Carbenoxolone disodium

Catalog No. T0992 CAS 7421-40-1

Synonyms: Bioral, Duogastrone, 甘珀酸钠, Biogastrone

Carbenoxolone disodium salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.

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Carbenoxolone disodium, CAS 7421-40-1

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Bioral, Duogastrone, 甘珀酸钠, Biogastrone
Molecular Weight	614.72
Formula	C34H48Na2O7
CAS No.	7421-40-1

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: 162.7 mM

DMSO: 37.4 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Hausmann W, Tárnoky AL. Br J Pharmacol ChemOthers. 1966 Feb;26(2):412-20. 2. Zhang H, Wei Q, Gao Z, et al. . G protein-coupled receptor 30 mediates meiosis resumption and gap junction communications downregulation in goat cumulus-oocyte complexes by 17β-estradio [J]. Journal of steroid biochemistry and molecular biology. 2019 Mar;187:58-67.

Citations

1. Zhang H, Li C, Wen D, et al. Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply. Redox Biology. 2022 Feb;49:102215. doi: 10.1016 2. Zhang H, Wei Q, Gao Z, et al. G protein-coupled receptor 30 mediates meiosis resumption and gap junction communications downregulation in goat cumulus-oocyte complexes by 17β-estradio. Journal of Steroid Biochemistry and Molecular Biology. 2019, 187: 58-67

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library DNA Damage & Repair Compound Library Immunology/Inflammation Compound Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Anti-COVID-19 Compound Library Cytoskeletal Signaling Pathway Compound Library Nonsteroidal Anti-Inflammatory Compound Library Approved Drug Library Anti-Cancer Drug Library

Related Products

Related compounds with same targets

TAT-Gap19 acetate Gap19 Gap 27 Carbenoxolone Gap 26 Danegaptide Hydrochloride Rotigaptide TFA(355151-12-1 free base) Larazotide acetate

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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