oca — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T83858	Tauro-Obeticholic Acid sodium	Tauro-6-Ethylchenodeoxycholic Acid,Tauro-6-Ethyl-CDCA,Obeticholic Acid Taurine Conjugate,Tauro-OCA,T-ECDCA
	Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid. This compound undergoes taurine conjugation in the liver to...
T1684	Nitisinone	NTBC,SC0735,Nitisone	Others , Reactive Oxygen Species
	Nitisinone (SC0735)(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.		Others , Reactive Oxygen Species
T2163	Dihydrocapsaicin	CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide	Others , TRP/TRPV Channel
	Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...		Others , TRP/TRPV Channel
TQ0038	Brensocatib	AZD7986,INS 1007	Proteasome
	Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively).		Proteasome
T34866	Thymocartin	Thymocartinum,TP 4,Thymopoietin II (32-35),RGH 0206
	Thymocartin (RGH 0206) is a fragment 32-35 of the naturally occurring thymic factor (thymopoietin).Thymocartin is used in the study of immunodeficiency diseases.
T10824	Cis-Urocanic acid	cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid	5-HT Receptor
	cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.		5-HT Receptor
TN7235	4-methoxylonchocarpin		TNF , NF-κB
	4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TNF expression by inhibiting the binding of LPS to TLR4 in ma...		TNF , NF-κB
T32098L	Homocarnosine acetate		GABA Receptor , Endogenous Metabolite
	Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition o...		GABA Receptor , Endogenous Metabolite
T23109	3,5-Dinitrocatechol		Transferase
	OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.		Transferase
T23071	Nitrocaramiphen hydrochloride		AChR
	M1 muscarinic antagonist		AChR
T30293	Bamocaftor	VX-659	CFTR
	Bamocaftor is a CFTR channel (DeltaF508-CFTR mutation) corrector for CF transmembrane conductance regulators designed to restore F508del-CFTR protein function. Combined use of tezacaftor and VX-561 for the treatment of c...		CFTR
T31716	Etidocaine Hydrochloride	W-19053,Duranest,W19053,W 19053	Sodium Channel
	Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.		Sodium Channel
T39598	4-Chlorocatechol		Others
	4-Chlorocatechol, a significant degradation product of 4-chloro-2-aminophenol (4C2AP), serves as a substrate for both catechol 1,2-dioxygenases and chlorocatechol dioxygenase [1] [2].		Others
T0924	Benzocaine		Others , MRP , Sodium Channel
	Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.		Others , MRP , Sodium Channel
T8422	DIETHYLDITHIOCARBAMIC ACID COPPER SALT		Others
	DIETHYLDITHIOCARBAMIC ACID COPPER SALT is a widely used industrial compound. It has been used as a chelating agent in various biochemical and physiological experiments, including experiments involving metals, proteins, a...		Others
T6782L	Benzocaine xHCl(94-09-7(free base))		Sodium Channel
	Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).		Sodium Channel
T0796	Prilocaine hydrochloride	Prilocaine HCl,Propitocaine hydrochloride,Xylonest	ATPase , Sodium Channel
	Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions.		ATPase , Sodium Channel
T16778	Rocastine	AHR-11325	Histamine Receptor
	Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.		Histamine Receptor
T13177L	Tocainide		Sodium Channel
	Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.		Sodium Channel
TQ0309	Glaucocalyxin B		Autophagy
	Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).		Autophagy