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Rocastine

Catalog No. T16778 CAS 91833-49-7

Synonyms: AHR-11325

Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.

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Rocastine, CAS 91833-49-7

Pack Size	Availability	Price/USD	Quantity
1 mg	In stock	$ 700.00
5 mg	In stock	$ 1,800.00

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Purity: 98.26%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.

In vivo

Rocastine is effective with a 15-minute pretreatment time (PD50 = 0.13 mg/kg) as it is with a 1-hour pretreatment time (PD50 = 0.12 mg/kg). In protecting guinea pigs from collapse induced by aerosolized antigen, rocastine demonstrates approximately 36 times more potency than diphenhydramine and is as potent as oxatomide and terfenadine. At doses in vast excess (150 times) of its antihistaminic dose, rocastine does not alter the EEG of cats, nor does it potentiate yohimbine toxicity in mice[1].

Synonyms	AHR-11325
Molecular Weight	265.37
Formula	C13H19N3OS
CAS No.	91833-49-7

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Nolan JC, et al. Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine. Agents Actions. 1989 Aug;28(1-2):53-61.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Rocastine 91833-49-7 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor AHR11325 AHR 11325 AHR-11325 inhibitor inhibit

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