Powder: -20°C for 3 years | In solvent: -80°C for 1 year
cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 219.00 | |
5 mg | In stock | $ 463.00 | |
10 mg | In stock | $ 683.00 | |
25 mg | In stock | $ 1,070.00 | |
50 mg | In stock | $ 1,450.00 | |
100 mg | In stock | $ 1,950.00 | |
500 mg | In stock | $ 3,890.00 |
Description | cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor. |
In vitro | Treatment with 100 μg/mL cis-Urocanic acid completely suppresses IL-6 and IL-8 secretion decreases caspase-3 activity and improves cell viability against UV-B irradiation. No significant effects on IL-6 or IL-8 secretion, caspase-3 activity, or viability of the non-irradiated cells are observed with 100 μg/mL cis-Urocanic acid in both cell types [1]. |
Synonyms | cis-UCA, (Z)-Imidazole-4-acrylic acid, (Z)-Urocanic acid, (E)-Urocanic acid, (Z)-3-(1H-Imidazol-5-yl)acrylic acid |
Molecular Weight | 138.12 |
Formula | C6H6N2O2 |
CAS No. | 7699-35-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 40 mg/mL (289.6 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
cis-Urocanic acid 7699-35-6 GPCR/G Protein Neuroscience 5-HT Receptor cis-UCA (Z)-Imidazole-4-acrylic acid Imidazole-4-acrylic acid Urocanic acid 3-(1H-Imidazol-5-yl)acrylic acid (Z)-Urocanic acid (E)-Urocanic acid (Z)-3-(1H-Imidazol-5-yl)acrylic acid inhibitor inhibit