nasal — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0042	Xylometazoline hydrochloride	Xylometazoline HCl	Adrenergic Receptor
	Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant.		Adrenergic Receptor
T38236	2′-Deoxy-2′-fluoroguanosine		Nucleoside Antimetabolite/Analog , Influenza Virus
	2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respirator...		Nucleoside Antimetabolite/Analog , Influenza Virus
T4S0878	Prunetin	Prunusetin	ERK , Dehydrogenase , NF-κB
	1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...		ERK , Dehydrogenase , NF-κB
T4563	Thonzylamine	neohetramine	Histamine Receptor
	Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhin...		Histamine Receptor
T0397	Tetrahydrozoline	Tetryzolin,Tetryzoline	Adrenergic Receptor
	Tetrahydrozoline (Tetryzoline), an alpha agonist, have an effect on the constriction of conjunctival blood vessels. This contributes to relieve the redness of the eye resulted from minor ocular irritants.		Adrenergic Receptor
T22033	ARC 239 dihydrochloride		Norepinephrine
	ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively).		Norepinephrine
T6703	Tetrahydrozoline hydrochloride	Murine Plus,Tetryzoline hydrochloride,Tyzine,Tetrahydrozoline HCl	Adrenergic Receptor
	Tetrahydrozoline hydrochloride (Murine Plus) is an imidazoline derivative with alpha receptor agonist activity.		Adrenergic Receptor
T0335	Sodium salicylate	Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt	Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
	Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.		Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
T26009	Quazolast	RHC-3988,RHC 3988,RHC3988	Others
	Quazolast (RHC 3988) is a potent mediator release inhibitor and is a control against ragweed antigenic nasal challenge. quazolast is superior to placebo in preventing nasal congestion and nasal itching following ragweed ...		Others
T71012	Nemazoline Free Base
	Nemazoline Free Base is a nasal decongestant. It has alpha 1-agonist/alpha 2-antagonist activity and was more effective and long-acting than oxymetazoline on canine nasal mucosa, in-vitro and in-vivo. Upon intranasal adm...
T3612	Carbocisteine	Carbocysteine,Broncodeterge,Mucodyne,S-Carboxymethyl-L-cysteine	Others
	Carbocisteine (Mucodyne) is commonly used as an anti-infective nasal spray with mucolytic and expectorant effects.		Others
TN1610	Epimagnolin A		Parasite
	Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasal congestion.		Parasite
T0113	Mebhydrolin napadisylate	Incidal,Diazolin,Mebhydroline 1,5-naphthalenedisulfonate salt,Omeril,Diazoline	5-HT Receptor , AChR , Histamine Receptor
	Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.		5-HT Receptor , AChR , Histamine Receptor
T1287	Synephrine	Oxedrine	Endogenous Metabolite , Adrenergic Receptor
	Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.		Endogenous Metabolite , Adrenergic Receptor
T4764	5-Methoxy-5-oxopentanoic acid	mono-Methyl glutarate,METHYL HYDROGEN GLUTARATE	Others , Endogenous Metabolite
	5-Methoxy-5-oxopentanoic acid (mono-Methyl glutarate) is a metabolite of dibasic esters(DBEs) by nasal respiratory and olfactory mucosae in vitro demonstrated that hydrolysis of DBEs yields mainly the monomethyl esters (...		Others , Endogenous Metabolite
T21404	Fluticasone furoate	Veramyst,Allermist,Avamys,Fluticasone furoate	Glucocorticoid Receptor
	Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure...		Glucocorticoid Receptor
T21390	Fexofenadine	Carboxyterfenadine,Telfast,MDL 16.455,Allegra	Histamine Receptor
	Fexofenadine (Carboxyterfenadine), an antihistamine pharmaceutical drug, is used to treat allergy symptoms, such as nasal congestion, hay fever, and urticaria. Compared to first-generation antihistamines, Fexofenadine is...		Histamine Receptor
T35455	N-Nitrosodiethylamine	Diethylnitrosamine,NDEA	DNA/RNA Synthesis
	N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso...		DNA/RNA Synthesis
T0900	Cetylpyridinium chloride monohydrate	Hexadecylpyridinium chloride monohydrate	Antibacterial , Antibiotic
	Cetylpyridinium chloride monohydrate (Hexadecylpyridinium chloride monohydrate) , a cationic quaternary ammonium compound, is used in certain classes of throat sprays, mouthwashes, lozenges, toothpaste, nasal sprays, and...		Antibacterial , Antibiotic
T69341	Tramazoline hydrochloride
	Tramazoline hydrochloride is commonly used in nasal spray as a nasal decongestant by acting as an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.