mbr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T20971	Mefluidide	VEL3973,VEL-3973,VEL 3973,MBR 12325
	Mefluidide is a biochemical.
T2371	Emapunil	AC-5216,XBD-173	Others
	Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.		Others
T36848	Combretastatin A-1	Combretastatin A1	Akt , Microtubule Associated
	Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/β-catenin pathway, and...		Akt , Microtubule Associated
T77752	HMBR	4-Thiazolidinone, 5-[(4-hydroxy-3-methylphenyl)methylene]-2-thioxo-, (5Z)-	Others
	HMBR are not fluorescent by themselves, but when combined with Y-FAST, they emit yellow light when excited by blue light.		Others
T13514	5-MethoxyPinocembroside		Others
	5-MethoxyPinocembroside is a flavonoid isolated from leaves of Moringa oleifera.		Others
T6234	Ambroxol hydrochloride	Mucosolvan,Mucoangin,Ambroxol HCl	Sodium Channel , Autophagy
	Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.		Sodium Channel , Autophagy
T6212	Combretastatin A4	CA4,CRC 87-09	Microtubule Associated
	Combretastatin A4 (CA4) is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).		Microtubule Associated
T2992	Pinocembrin	5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone	NF-κB , Reactive Oxygen Species , Antibacterial , Autophagy
	Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.		NF-κB , Reactive Oxygen Species , Antibacterial , Autophagy
T0920	Ambroxol	Ambroxolum,NA-872	P450 , Autophagy
	Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a muco...		P450 , Autophagy
T9908	Pembrolizumab		PD-1/PD-L1
	Pembrolizumab is a humanized monoclonal antibody inhibiting the PD-1 receptor and the first in the class of agents called the HER2 dimerization inhibitors that impairs the ability of HER2 to bind to other members of the ...		PD-1/PD-L1
T2S1682	Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside	Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside	Amylase
	Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml.		Amylase
T13140	Umbralisib R-enantiomer	TGR-1202 R-enantiomer,RP5264 R-enantiomer	PI3K
	Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the in...		PI3K
T7479	Ambroxide	(-)-Ambroxide	Others
	Ambroxide ((-)-Ambroxide) is a naturally product,is one of the key constituents of ambergris.		Others
TP1286	Carcinoembryonic Antigen CEA		Others
	Carcinoembryonic antigen (CEA) is a protein that is present in certain tissues of a developing baby (fetus)		Others
T2711	Chembridge-5861528	TCS 5861528	TRP/TRPV Channel
	Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM, respectively.		TRP/TRPV Channel
TN2078	Pinocembrin chalcone	2',4',6'-Trihydroxychalcone,Pinocembrinchalcone	Calcium Channel , Tyrosinase , Antibacterial , Antifection
	Pinocembrin chalcone is an inhibitor of tyrosinase with antimutagenic effects. Pinocembrin chalcone can be used in studies about the prevention of gastric ulcers.		Calcium Channel , Tyrosinase , Antibacterial , Antifection
T28750	Sembragiline	RG-1577,EVT-302,RO-4602522,RO4602522,RG1577,EVT302	MAO
	Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).		MAO
TN2077	(+/-)-Pinocembrin	NSC 43318,(±)-5,7-Dihydroxyflavanone	GPR , Others
	(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.		GPR , Others
T5710	Pinocembrin-7-O-β-D-glucopyranoside	Pinocembrin 7-O-beta-D-glucoside	Others
	Pinocembrin-7-O-β-D-glucopyranoside (Pinocembrin 7-O-beta-D-glucoside) is a natual product isolated from Penthorum chinense Pursh.		Others
T1655	Ambrisentan	BSF-208075,BSF 208075,LU 208075	Endothelin Receptor
	Ambrisentan (BSF 208075) is an endothelin receptor antagonist used in the therapy of pulmonary arterial hypertension (PAH). Ambrisentan has been associated with a low rate of serum enzyme elevations during therapy but ha...		Endothelin Receptor