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Ambroxol

Catalog No. T0920   CAS 18683-91-5
Synonyms: Ambroxolum, NA-872

Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body's natural defense mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants act as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Ambroxol Chemical Structure
Ambroxol, CAS 18683-91-5
Pack Size Availability Price/USD Quantity
50 mg In stock $ 30.00
100 mg In stock $ 39.00
200 mg In stock $ 55.00
500 mg In stock $ 91.00
1 mL * 10 mM (in DMSO) In stock $ 39.00
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Purity: 99.95%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body's natural defense mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants act as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.
Synonyms Ambroxolum, NA-872
Molecular Weight 378.1
Formula C13H18Br2N2O
CAS No. 18683-91-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 69 mg/mL(182.5 mM)

TargetMolReferences and Literature

1. Preissner S, et al. Nucleic Acids Res. 2010, 38(Database issue):D237-43.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Oxidation-Reduction Compound Library Bioactive Compound Library Anti-Metabolism Disease Compound Library Autophagy Compound Library FDA-Approved & Pharmacopeia Drug Library Metabolism Compound Library Bioactive Compounds Library Max

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Keywords

Ambroxol 18683-91-5 Autophagy Metabolism P450 inhibit Inhibitor NA872 Glucosidase GCase Gaucher disease neuronopathic chaperone Parkinson expectorant Ambroxolum Bromhexine NA 872 NA-872 glucocerebrosidase inhibitor

 

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