20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T83879 | 1-Arachidoyl Lysophosphatidic Acid sodium | 1-Arachidoyl LPA,LPA(20:0),1-Eicosanoyl-Lysophosphatidic Acid | |
1-Arachidoyl lysophosphatidic acid (1-arachidoyl LPA), a glycerophospholipid with arachidic acid at the sn-1 position, functions as an agonist for lysophosphatidic acid receptor 1 (LPA1). It effectively induces calcium m... | |||
T77789 | Oleoyl-L-alpha-lysophosphatidic acid sodium salt | LPA sodium salt | |
Oleoyl-L-alpha-lysophosphatidic acid sodium salt is an essential cell membrane biosynthetic metabolite that mediates signal transduction by interacting with G protein-coupled receptors (GPCRs) (ie, LPA receptors). It is ... | |||
T31101 | CRT0273750 | CRT 0273750,CRT-0273750 | PDE |
CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM. | |||
T23438 | TC LPA5 4 | LPA Receptor | |
TC LPA5 4 is a LPA5 receptor antagonist. | |||
T22834 | H2L 5765834 | LPA Receptor , LPL Receptor | |
H2L 5765834 is a lysophosphatidic acid receptors antagonist | |||
T15785 | LPA1 receptor antagonist 1 | LPA1 R antagonist 1 | LPA Receptor |
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis. | |||
T36907 | 1-Oleoyl Lysophosphatidic Acid | Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid | |
1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through ... | |||
T11533 | Z-HA155 | CS-963 | PDE |
Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM. | |||
T83772 | 1-Linoleoyl Lysophosphatidic Acid sodium | 1-Linoleoyl-2-hydroxy-sn-glycero-3-PA,LPA(18:2),PA(18:2(9Z,12Z)/0:0),1-Octadecadienoyl-2-hydroxy-sn-glycero-3-phosphate,18:2 Lyso PA,1-Octadecadienoyl-2-hydroxy-sn-glycero-3-PA,PA(18:2/0:0),1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate,1-Linoleoyl LPA | |
1-Linoleoyl lysophosphatidic acid (1-linoleoyl LPA), a glycerophospholipid with linoleic acid at its sn-1 position, acts as an LPA2 receptor agonist and is the predominant LPA form in both mouse and human plasma. This co... | |||
T11875 | LPA2 antagonist 2 | LPA Receptor | |
LPA2 antagonist 2 is >480-fold more selective than LPA3 (IC50 of 13.85 μM).LPA2 antagonist 2 is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM. | |||
T21654 | 1-Oleoyl lysophosphatidic acid sodium | 1-Oleoyl lysophosphatidic acid sodium salt | LPA Receptor |
1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2 | |||
T15786 | LPA2 antagonist 1 | Hydroxylase | |
LPA2 antagonist 1 is an LPA2 antagonist (IC50: 17 nM). | |||
T1606 | Fasudil | HA-1077,AT877 | ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy |
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK. | |||
T3060 | Fasudil hydrochloride | Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877 | ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy |
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively. | |||
TP2056L | Acetyl-Calpastatin (184-210)(human) acetate | Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base ) | Cysteine Protease |
Acetyl-Calpastatin (184-210)(human) acetate is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively. | |||
T4628 | Seladelpar | MBX 8025 | PPAR |
Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia. | |||
T0927 | Butylparaben | Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate | Endogenous Metabolite , Antibacterial , Antibiotic |
Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity. | |||
T5670 | Isobutylparaben | Others , Antibacterial | |
Isobutylparaben is a preservative and preservative insecticide. | |||
T3S2105 | N-Benzylpalmitamide | Macamide 1,N-Benzylhexadecanamide | Others , FAAH , Autophagy |
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders... | |||
T3334 | Velpatasvir | GS-5816 | HCV Protease , SARS-CoV |
Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 d... |