lep — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1305	LEP(116-130)(mouse)		Others
	Leptin (116-130),mouse(C64H109N19O24S),a peptide with the sequence Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2. Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake an...		Others
TP1305L	LEP(116-130)(mouse)TFA(258276-95-8 free base)		Complement System
	LEP(116-130)(mouse) is a synthetic leptin peptide fragment.		Complement System
T5297	3-Indolepropionic acid	Indolepropionic acid,IPA,indole-3-propionic acid	Antioxidant , Reactive Oxygen Species , Endogenous Metabolite
	3-Indolepropionic acid (Indolepropionic acid) is shown to be a powerful antioxidant with potential in the treatment for Alzheimer’s disease.
T25664	Lepidiline A	Macaline A	Others
	Lepidiline A (Macaline A) is a flavonoid lignin with anti-inflammatory activity. Lepidiline A showed cytotoxic activity against HL-60 cells with IC50 of 32.3 μM. It is the active ingredient of Lepidium meyenii Walpers, a...		Others
T15735	Leptomycin B	CI 940,LMB	CRM1 , Antibiotic , Antifungal
	Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ...		CRM1 , Antibiotic , Antifungal
T38815	Millepachine		Apoptosis
	Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.		Apoptosis
T32088	Sovleplenib	HMPL 523,HMPL523,HMPL-523	Syk
	Sovleplenib (HMPL523) is an orally available, selective and potent inhibitor of the splenic tyrosine kinase SYK with an IC50 of 25 nM.Sovleplenib has antitumor activity and may be used in studies of immune thrombocytopen...		Syk
T29856	Aleplasinin	PAZ 417,PAZ417,PAZ-417	PAI-1
	Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies...		PAI-1
T4S1999	Valepotriate	Valtrate	Apoptosis , HIV Protease
	Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and antitumor agents, they are very potent cytotoxic agen...		Apoptosis , HIV Protease
T67922	Lepidiline C		Others
	Lepidiline C is a novel imidazoles alkaloids extracted from the root of Lepidium meenii Walpers of the brassaceae family. It has shown cytotoxic activity against HL-60 cells (IC50:27.7 μM).		Others
TN1141	Isodeoxyelephantopin		NF-κB , Reactive Oxygen Species , Autophagy
	Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibit...		NF-κB , Reactive Oxygen Species , Autophagy
T34383	Rofleponide		Glucocorticoid Receptor
	Rofleponide is a synthetic glucocorticosteroid with a high affinity for the rat thymus glucocorticoid receptor.		Glucocorticoid Receptor
T0453	Phenylephrine hydrochloride	NCI-c55641,Phenylephrine HCl,(R)-(-)-Phenylephrine hydrochloride	Endogenous Metabolite , Adrenergic Receptor
	Phenylephrine hydrochloride (NCI-c55641) is a selective agonist of the α1-adrenergic receptor.		Endogenous Metabolite , Adrenergic Receptor
T17310	Phenylephrine	L-Phenylephrine,(R)-(-)-Phenylephrine	Adrenergic Receptor
	Phenylephrine ((R)-(-)-Phenylephrine) is a selective α1-adrenoceptor agonist ( pKi: 5.86, 4.87 and 4.70 for α1D, α1B, and α1A receptors respectively).		Adrenergic Receptor
TN1079	Deoxyelephantopin		NF-κB
	Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling		NF-κB
T2937	4'-Demethylepipodophyllotoxin	4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin	Microtubule Associated
	4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.		Microtubule Associated
TN1858	Leptomerine		AChE
	Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity.		AChE
T37089	Iclepertin	BI-425809	GlyT
	Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin...		GlyT
T126471	3'-Deoxy-4-O-methylepisappanol
	3'-Deoxy-4-O-methylepisappanol is a useful organic compound for research related to life sciences and the catalog number is T126471.
T125044	Lepidoside
	Lepidoside is a useful organic compound for research related to life sciences. The catalog number is T125044 and the CAS number is 32311-68-5.