Search Result

Search Results for " f5 "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T65853	Fmoc-Phe(F5)-OH
	Fmoc-Phe(F5)-OH is an amino acid derivative and has a wide range of applications in life science related research.
T25097	Antibiotic tan-592B	TAN592B,Cephabacin F5 hydrochloride,TAN 592B,TAN-592B
	Antibiotic tan-592B is an antibiotic agent.
T13992	CHF5407	SVT-47060	AChR
	CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on bronchospasm and may be used in the study of respiratory disorders.CHF...		AChR
T24784	SF5	SF-5,SF 5	Apoptosis
	SF5 is an inhibitor of the apoptosis pathway. Which is through the JNK-p53-caspase apoptotic cascade.		Apoptosis
T8499	ECF506		Src
	eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)		Src
T10773	CF53		Epigenetic Reader Domain , CDK
	CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT B...		Epigenetic Reader Domain , CDK
T76513	2F5 epitope
	The 2F5 epitope, a peptide gp41 (659-671), encompasses the complete sequential epitope recognized by one of the three broadly neutralizing antibodies against a wide range of primary HIV-1 isolates. This epitope is unique...
T62140	HF50731
	HF50731 is a potent antagonist of CXCR4. HF50731 has a strong binding affinity for CXCR4 (IC50: 19.8 nM). HF50731 utilizes the CXCR4 co-receptor and effectively inhibits calcium mobilization (IC50: 119.2 nM), cell migrat...
T12217	NF546		Others
	NF546 is a selective agonist of non-nucleotide P2Y11(pEC50 of 6.27).		Others
T70338	Lu AF58786
	Lu AF58786 is a novel potent and selective inhibitor of LRRK2, inhibiting LRRK2 WT, the overactive variant G2019S, and the resistant mutant A2016T56 at 12 nM, 19 nM and 93 nM, respectively.
T76659	Acetyl-PHF5 amide
	Acetyl-PHF5 amide is a tau peptide with amyloidogenic properties. It can undergo polymerization to form filamentous structures [1].
TP2130L	Rac1 Inhibitor F56, control peptide acetate	Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base)	Rho
	Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction.		Rho
TP2130	Rac1 Inhibitor F56, control peptide
	Control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction.
T78079	NF546 hydrate		P2Y Receptor
	NF546 (hydrate), a selective non-nucleotide P2Y11 agonist, exhibits a pEC50 value of 6.27 and induces interleukin-8 secretion from human monocyte-derived dendritic cells [1].		P2Y Receptor
T25760	Lu AF58801	AF58801,AF-58801,Lu-AF58801,LuAF58801,AF 58801
	Lu AF58801 is a brain penetrant positive allosteric and selective modulator of alpha-7 nicotinic acetylcholine receptors.
T26385	41F5	41F 5,41F-5
	41F5 is anti-fugal agent. 41F5 is highly active against Histoplasma yeast (MIC50 0.4-0.8 μM). 41F5 has fungistatic activity against Histoplasma yeast with a 50% inhibitory concentration (IC50) of 0.87 μM, and has the gre...
T71890	F5446
	F5446 is a SUV39H1 inhibitor. F5446 has an EC50 of 0.496 μmol/L for SUV39H1 enzymatic activity. H3K9me3 was enriched in the promoters of GZMB, PRF1, FASLG, and IFNG in quiescent T cells. F5446 inhibited H3K9me3, thereby ...
T41149	BOP-JF549	BOP-JF549
	BOP-JF549 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP conjugated to Janelia Fluor® 549. Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and pho...
T64587	P44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R
	p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R is a useful organic compound for research related to life sciences and the catalog number is T64587.
T29686	AF53	AF 53,AF-53
	AF53 is an kind of alpha-L-arabinofuranosidase containing a noncatalytic xylan-binding domain.
T29147	VUF5834	VUF-5834,VUF 5834
	VUF5834 is a full inverse agonist of CXCR3 N3.35A.
T70719	MLAF50
	MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.
T27861	LUF5831	LUF 5831,LUF-5831
	LUF5831 is an agonist of adenosine A1 receptor.
T75383	Anti-α-Tubulin Antibody, AF555 conjugate
	Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for the specific detection of tubulin (Ex/Em: 554/567 nm) [1].
T35883	RNF5 inhibitor inh-02	RNF5 inhibitor inh-02
	RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation...
T18593	GNF5-amido-Me	PROTAC ABL binding moiety 2	Others
	GNF5-amido-Me, the moiety based on GNF5 (ABL inhibitor),binds through a linker to the IAP ligand forming SNIPER[1].		Others
T27609	INF55
	INF55 inhibits NorA efflux pump.
T27862	LUF5981	LUF-5981,LUF 5981
	LUF5981 is a selective agonist of human adenosine A1 receptor.
T63661	HF51116
	HF51116 is a potent antagonist of XCR4. HF51116 significantly antagonizes SDF-1α-induced cell migration, calcium mobilization and CXCR4 internalization, and inhibits HIV-1 infection using CXCR4. HF51116 has shown investi...
T38296	Alamethicin F50	Alamethicin F50
	Alamethicin F50 is a peptaibol isolated from Trichoderma. It is a polymer of 20 amino acids that includes modified and non-proteinogenic amino acids. Alamethicin F50 is a mixture of 13 different peptides, with the most a...
T61307	LUF5771
	LUF5771 is a highly potent allosteric inhibitor of recombinant luteinizing hormone (recLH) and Org 43553. It exhibits partial activation of the LH receptor with low efficacy [1].
T81849	MAT-POS-e194df51-1		SARS-CoV
	MAT-POS-e194df51-1 is an orally active, non-covalent, non-peptide inhibitor of the SARS-CoV-2 main protease (M^pro) with an IC_50 of 37nM. It exhibits cytotoxicity, with EC_50 values of 64nM in A549-ACE2-TMPRSS2 cells an...		SARS-CoV
T31190	Dafphedyn
	Dafphedyn, [D-Ala2, (F5) Phe4]-dynorphin 1-13-NH2 (DAFPHEDYN) is an effective analog of strong endorphin 1-13 and produces diuretic and deep analgesia when administered intravenously in rats.

Compounds

Synonym: TAN592B,Cephabacin F5 hydrochloride,TAN 592B,TAN-592B

Target: Epigenetic Reader Domain, CDK

Rac1 Inhibitor F56, control peptide acetate

TP2130L

Synonym: Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base)

Target: Rho

Rac1 Inhibitor F56, control peptide

Synonym: AF58801,AF-58801,Lu-AF58801,LuAF58801,AF 58801

p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R

Synonym: VUF-5834,VUF 5834

Synonym: LUF 5831,LUF-5831

Target:

Anti-α-Tubulin Antibody, AF555 conjugate

T75383

Synonym:

Target:

RNF5 inhibitor inh-02

T35883

Synonym: RNF5 inhibitor inh-02

Target:

GNF5-amido-Me

T18593

Synonym: PROTAC ABL binding moiety 2

Synonym: LUF-5981,LUF 5981

Synonym: Alamethicin F50

Cat No.	Product Name	Targets
TN1684	Ginsenoside F5	Apoptosis
	Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway	Apoptosis
TN4162	Goshonoside F5	IκB/IKK , p38 MAPK , TNF , NOS , NF-κB , COX , Prostaglandin Receptor , JNK
	Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.

Natural Products

Target: IκB/IKK, p38 MAPK, TNF, NOS, NF-κB, COX, Prostaglandin Receptor, JNK

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-01107	Coagulation factor V Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Coagulation factor V Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-00455	SLAMF5 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based ...
TMPJ-00228	SLAMF5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	SLAMF5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 40-50 KDa and the accession number is Q9UIB8.
TMPY-06398	SARS-CoV-2 Spike S1+S2 Protein (E484K & F565L & D614G & V1176F, His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1+S2 Protein (E484K & F565L & D614G & V1176F, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.35 kDa and the accession number is A0A6G7K2L4.
TMPY-03868	ARF5 Protein, Human, Recombinant (His)	Human	E. coli
	ARF5, also known as ADP-ribosylation factor 5, belongs to the small GTPase superfamily, Arf family. Members of this family stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular traff...
TMPY-00847	IL-36RN/IL-1F5 Protein, Human, Recombinant	Human	E. coli
	IL-36RN/IL-1F5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.1 kDa and the accession number is Q9UBH0.
TMPJ-00229	SLAMF5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SLAMF5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-43 KDa and the accession number is Q9UIB8.
TMPJ-01110	IRF5 Protein, Human, Recombinant (His)	Human	E. coli
	Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it ...
TMPH-02175	TAF5L Protein, Human, Recombinant (GST)	Human	E. coli
	Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex....
TMPY-03184	EIF5 Protein, Human, Recombinant (GST)	Human	E. coli
	EIF5 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 44.1 kDa and the accession number is P55010.
TMPY-02961	PANP/C12orf53 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	C12orf53 is mainly expressed in adult brain and cerebellum. It also can be detected in fetal brain and virtually no expression in spleen, heart, kidney, liver and dorsal ganglion relative to brain. C12orf53 acts as a lig...
TMPH-02209	TRAF5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation o...
TMPY-03795	EIF5A2 Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted i...
TMPY-04275	IL-36RN/IL-1F5 Protein, Mouse, Recombinant	Mouse	E. coli
	IL-36RN/IL-1F5 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 kDa and the accession number is Q9QYY1.
TMPY-06399	SARS-CoV-2 Spike S1 Protein (E484K & F565L & D614G & V1176F, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (E484K & F565L & D614G & V1176F, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.37 kDa and the accession number is A0A6G7K2L4.
TMPY-04108	EIF5A Protein, Human, Recombinant (His)	Human	E. coli
	EIF5A Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.9 kDa and the accession number is P63241-1.
TMPH-00038	Thrombin-like enzyme contortrixobin Protein, Agkistrodon contortrix, Recombinant (His & Myc)	Agkistrodon contortrix	E. coli
	Thrombin-like snake venom serine protease that cleaves beta chain of fibrinogen (FGB), releasing fibrinopeptide B. Has a coagulant activity activating blood coagulation factors V (F5) and XIII (F13A1). Thrombin-like enzy...
TMPY-03400	DCBLD1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Discoidin, also known as DCBLD1, contains 1 CUB domain, 1 F5/8 type C domain and 1 LCCL domain. It is a 715 amino acid single-pass membrane protein. Discoidin has a discoidin I-like domain which shares a common C-termina...
TMPY-01695	CASPR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CNTNAP2/CASPR2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor re...