Shopping Cart
- Remove All
Your shopping cart is currently empty
eCF506
🥰Excellent
Catalog No. T8499Cas No. 1914078-41-3
eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)
eCF506
🥰Excellent
Purity: 98.16%
Catalog No. T8499Cas No. 1914078-41-3
eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $40 | In Stock | |
| 2 mg | $57 | In Stock | |
| 5 mg | $85 | In Stock | |
| 10 mg | $126 | In Stock | |
| 25 mg | $207 | In Stock | |
| 50 mg | $369 | In Stock | |
| 100 mg | $531 | In Stock |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreBatch Information
Select Batch
Purity:98.16%
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
| Description | eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM) |
| Targets&IC50 | Src:< 0.5 nM), MDA-MB-231 cells:9 nM (EC50), yes:2.1 nM |
| In vitro | eCF506 can inhibit tyrosine kinase Src with IC50 value less than 0.5 nM. |
| In vivo | METHODS: Immunodeficient Rag2-Il2rg double knockout mice were implanted with PX459v2 and ILK gRNA 2 tumors and then given bosutinib (75 mg/kg) or eCF506 (40 mg/kg) once daily by oral gavage, and tumor volume growth was observed. RESULTS eCF506 treatment completely blocked the growth of ILK gRNA and PX459v2 tumors in the mouse model. [2] |
| Molecular Weight | 510.63 |
| Formula | C26H38N8O3 |
| Cas No. | 1914078-41-3 |
| Smiles | COc1cc(ccc1NC(=O)OC(C)(C)C)-c1nn(CCN2CCC(CC2)N(C)C)c2ncnc(N)c12 |
| Relative Density. | 1.29 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 52.5 mg/mL (102.81 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.92 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy eCF506 | purchase eCF506 | eCF506 cost | order eCF506 | eCF506 chemical structure | eCF506 in vivo | eCF506 in vitro | eCF506 formula | eCF506 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.