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Search Results for " bms-a "

20

Compounds

Cat No. Product Name Synonyms Targets
T7512 BMS-191011 BMS-A Potassium Channel
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
T8542 BMS-345541 hydrochloride IκB/IKK
BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).
T30520 BMS-394136 BMS394136,BMS 394136,BMS394136;UNII-M694U7167K Potassium Channel
BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
T3462 BMS-582949 hydrochloride BMS-582949 HCl p38 MAPK , Autophagy
The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).
T21790 BMS 182874 hydrochloride Endothelin Receptor
BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.
T22277L BMS-P5 free base PAD
BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-...
T22192 BMS 195614 BMS614 Retinoid Receptor
BMS 195614 (BMS614) is a selective RAantagonist. BMS 195614 can bind to the RARα subunit.
T6249 Avagacestat BMS-708163 Gamma-secretase
Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
T2699 BMS 777607 BMS777607,BMS-777607,BMS 817378 c-Met/HGFR , TAM Receptor
BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.
T2610L BMS-599626 2HCL(714971-09-2 Free base) BMS 599626 dihydrochloride,BMS-599626 2HCL(714971-09-2 Free base),AC480 2HCl HER
BMS-599626 2HCL (AC480 2HCl) is a BMS-599626 derivative. BMS-599626 is an orally available and selective dual inhibitor of HER1 and HER2 with IC50s of 20 and 30 nM, respectively. BMS-599626 inhibits tumor cell proliferat...
T2419 BMS-794833 VEGFR , c-Met/HGFR
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.
T71394 BMS-823778
BMS-823778 is an orally available potent and selective inhibitor of 11-β-hydroxysteroid-dehydrogenase 1 (11βHSD-1). BMS-823778 is a potential therapeutic agent for type 2 diabetes mellitus (T2DM).
T8470 BMS-1001 PD-1/PD-L1
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
T3495 Tasimelteon VEC-162,BMS-214778 Melatonin Receptor , MT Receptor
Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.
T39654 Afimetoran BMS-986256 TLR
Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.
T8326 BMS-2 VEGFR , FLT , c-Met/HGFR
BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.
T14676 BMS-688521 Integrin
BMS-688521 BMS-688521 is an orally active and potent inhibitor of LFA-1/ICAM interaction, a small molecule antagonist of leukocyte function-associated antigen-1 (LFA-1), with potential anti-inflammatory activity.
T14681 BMS-935177 BTK
BMS-935177 is a reversible BTK inhibitor with IC50 value of 3 nM.
T60052 BMS-905 TLR
BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members. BMS-905 can be used in studies about the treatment of diseases such as psoriasis, arthritis, and lupus.
T21714 BMS453 BMS 453,BMS-189453 Retinoid Receptor
BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RAand a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
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TargetMol