whole — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9020	GSK620		Epigenetic Reader Domain
	GSK620 is a pan-BD2 inhibitor, which shows an anti-inflammatory phenotype in human whole blood with excellent broad selectivity, developability, and in vivo oral pharmacokinetics.GSK620 is highly selective for the BET-BD...		Epigenetic Reader Domain
T22408	Proflavine	3,6-Diaminoacridine	Antibacterial
	Proflavine (3,6-Diaminoacridine) (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria and is a topical antiseptic used mainly in wound dressings.		Antibacterial
T12997	SR-318		p38 MAPK , TNF
	SR-318 is a potent and highly selective inhibitor of p38 MAPK(IC50s of 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β, respectively), has anti-cancer and anti-inflammatory activity.		p38 MAPK , TNF
T8372	VU0134992	VU 0134992	Potassium Channel
	VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM		Potassium Channel
T13316	VU0134992 hydrochloride		Potassium Channel
	VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 µM).		Potassium Channel
T0438	Proflavine Hemisulfate	3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate	Others , Potassium Channel , DNA , Thrombin , Antibacterial , Autophagy
	Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and a...
T14975	CJ-42794	CJ-042794	Others
	CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-...		Others
T6658	SB-408124		OX Receptor
	SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.		OX Receptor
TN2079	(-)-Pinoresinol		Others , TNF , NF-κB , COX
	(-)-Pinoresinol is isolated from the whole plant of Serissa japonica (Thunb.) Thunb.		Others , TNF , NF-κB , COX
T32824	LM-1685	LM 1685,LM1685	COX
	LM-1685 is a potent and selective inhibitor of COX-2 IN human monocytes and whole blood with IC50 of 0.65µM and IC50 = 4.3μM, respectively, and is a potential compound for the treatment of inflammation.		COX
T3S0693	Blinin		Others
	Blinin, isolated from the whole plant of Conyza blinii, is used in folk medicine in the south-west of China.		Others
TN7077	Sinocrassoside C1		Others
	Sinocrassoside C1 is the methanolic extract of the whole plant of Sinocrassula indica (Crassulaceae), six new flavonol glycosides		Others
T31213	Dazmegrel	UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485	PPAR
	Dazmegrel (UK 38,485) is a potent and specific thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.		PPAR
T5730	MALTOHEXAOSE	Amylohexaose	Others , Endogenous Metabolite
	Maltohexaose (Amylohexaose) is a natural saccharide, and can be produced from amylose, amylopectin and whole starch.		Others , Endogenous Metabolite
T10866	Cot inhibitor-2		TNF , MAPK
	Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α production in human whole blood with an IC50 of 0.3 μM.		TNF , MAPK
T4367	Mycro 3	Mycro-3	c-Myc , Autophagy
	Mycro 3 is potent and selective for c-Myc in whole cell assays.		c-Myc , Autophagy
T77747	Adecatumumab	MT 201	Others
	Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer.		Others
T77018	Garadacimab	CSL312	Factor Xa
	Garadacimab (CSL312) is a potent whole-human IgG4 monoclonal antibody targeting activation factor XII (FXIIa). Garadacimab can be used to study hereditary angioedema.		Factor Xa
T76874	Erenumab	AMG-334	CGRP Receptor
	Erenumab is a whole-human monoclonal antibody. Erenumab inhibits calcitonin gene-related peptide (CGRP) receptors. Erenumab can be used to prevent migraine attacks.		CGRP Receptor
T2758	Madecassic acid	6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose	Others , TNF , COX , NO Synthase , Interleukin
	Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.		Others , TNF , COX , NO Synthase , Interleukin