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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8239 | Cromoglicic acid | Others | |
Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells. | |||
T4S0878 | Prunetin | Prunusetin | ERK , Dehydrogenase , NF-κB |
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit... | |||
T21404 | Fluticasone furoate | Veramyst,Allermist,Avamys,Fluticasone furoate | Glucocorticoid Receptor |
Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure... | |||
T3979 | Emedastine | LY188695,Emadine | Histamine Receptor |
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its... | |||
T0211 | Azelastine | Azelastina,Astelin,Azelastinum | SARS-CoV , Histamine Receptor |
Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer. | |||
T0861 | Tylosin tartrate | Antibacterial , Antibiotic | |
Tylosin tartrate, a macrolide antibiotic, is approved for the control of mycoplasmosis in poultry. | |||
T0118 | Mizolastine | SL 850324 | Histamine Receptor |
Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives. | |||
T4038 | Ectoine | THP(B),L-Ectoine | Others , Antibacterial |
Ectoine (L-Ectoine) is an osmoprotectant in a variety of microorganisms including halophilic and heterotrophic bacteria and non-halophilic bacteria such as the Streptomyces species, as well as E.coli. | |||
T6242 | Rupatadine Fumarate | Rinialer,Rupafin,Alergoliber | PAFR , Autophagy , Histamine Receptor |
Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM. | |||
T1003 | Tylosin | Fradizine,Tylosin A,Tylosine,Tylocine | Antibacterial , Antibiotic |
Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans. | |||
T0059 | Diphenylpyraline hydrochloride | 4-Diphenylmethoxy-1-methylpiperidine hydrochloride | Histamine Receptor |
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is used in the treatment of Parkinsonism.It is a first-generation antihistamine with anticholinergic effects, functions as a dopamine re... | |||
T1030 | Triprolidine hydrochloride monohydrate | Triprolidine hydrochloride | Histamine Receptor |
Triprolidine hydrochloride monohydrate is a histamine H1 antagonist used in allergic rhinitis, asthma. | |||
T3185 | R112 | (E)-Elafibranor | Syk |
R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase. | |||
T0211L | Azelastine hydrochloride | Optivar,Azelastine HCl,Allergodil,Astelin | SARS-CoV , Histamine Receptor |
Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity. | |||
T1269 | Tripelennamine hydrochloride | Pyribenzamine hydrochloride,Tripelennamine HCl,Pyribenzamine HCl | Histamine Receptor |
Tripelennamine hydrochloride (Pyribenzamine hydrochloride) is a histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. | |||
T3520 | Setipiprant | KYTH-105,ACT-129968 | GPR , Prostaglandin Receptor |
Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in vari... | |||
T0205 | Brompheniramine maleate | Dimotane,Rolabromophen,Brompheniramine hydrogen maleate,Dimetane | 5-HT Receptor , Histamine Receptor |
Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors. | |||
T0188 | Fluticasone (propionate) | CCI-187881,Fluticasone propionate | Glucocorticoid Receptor , Virus Protease , Estrogen/progestogen Receptor , Phospholipase , Endogenous Metabolite |
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist. | |||
T2335 | Ebastine | Ebastel,LAS-W 090,Ebastin,Kestine,RP64305 | Histamine Receptor |
Ebastine (Kestine) (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tiss... | |||
T0089 | Cetirizine dihydrochloride | P071,UCB P071,Cetirizine DiHCl | Histamine Receptor |
Cetirizine dihydrochloride (UCB P071) is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventiona... |