Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tripelennamine hydrochloride (Pyribenzamine hydrochloride) is a histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 33.00 | |
50 mg | In stock | $ 47.00 | |
100 mg | In stock | $ 68.00 | |
200 mg | In stock | $ 102.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | Tripelennamine hydrochloride (Pyribenzamine hydrochloride) is a histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. |
Targets&IC50 | H1 receptor:30 μM |
In vitro | In equines, intravenous administration of Tripelennamine HCl (0.5 mg/kg) significantly elevates standing mixed venous blood oxygen tension and hemoglobin-O2 saturation while increasing oxygen content in both arterial and mixed venous blood, leading to central nervous system stimulation, resulting in heightened alertness and anxiety. |
In vivo | In both human and rabbit liver microsomes, Tripelennamine inhibits the glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). |
Synonyms | Pyribenzamine hydrochloride, Tripelennamine HCl, Pyribenzamine HCl |
Molecular Weight | 291.82 |
Formula | C16H21N3·HCl |
CAS No. | 154-69-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 13 mg/mL (44.55 mM)
You can also refer to dose conversion for different animals. More
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Tripelennamine hydrochloride 154-69-8 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor Tripelennamine Pyribenzamine hydrochloride Tripelennamine HCl Inhibitor inhibit antihistaminic Pyribenzamine HCl rhinitis Pyribenzamine Hydrochloride allergic response conjunctivitis Endogenous Metabolite Tripelennamine Hydrochloride inhibitor