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20

Compounds

Cat No. Product Name Synonyms Targets
T8441 Lerisetron 5-HT Receptor
Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.
T3474 RO 46-8443 Endothelin Receptor
RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.
T1752 NS6180 Potassium Channel
NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.
T2626 SBC-115076 SBC115076 Others , Serine/threonin kinase
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
T5194 SPHINX31 Serine/threonin kinase
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
T35317 Zopolrestat CP 73850,CP73850,CP-73850,Zopolrestatum Reductase
Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).
T5329 Trandolapril Angiotensin-converting Enzyme (ACE)
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.
T8405 Vardenafil hydrochloride PDE
Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes
T0096 Vardenafil Vivanza,Levitra,Vardenafil hydrochloride PDE
Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemod...
T0293 Metyrapone NSC-25265,Su-4885 Others , P450 , Dehydrogenase , Autophagy
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
T3046 BMY 7378 dihydrochloride BMY7378 HCl Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
T29112 VPC171 VPC 171,VPC-171 Adenosine Receptor
VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).
T4097 Vardenafil hydrochloride trihydrate Vardenafil HCl Trihydrate,BAY38-9456 PDE
Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
T23044 N,N'-Dicyclohexylurea DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582 Epoxide Hydrolase
N,N'-Dicyclohexylurea (AURORA KA-3582) is a soluble epoxide hydrolase (sEH) inhibitor.
T0031L Ziprasidone hydrochloride CP-88059 hydrochloride,CP-88059,Ziprasidone HCl Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T4480 Vardenafil dihydrochloride Levitra,Vardenafil Hydrochloride PDE
Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
T27678 JNJ-39220675 JNJ39220675
JNJ-39220675, a selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.
T27252 ELB-139 ELB139
ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.
T34435 RU 47213 RU-47213,Itameline,RU47213 Others
RU 47213 can be used to inhibit scopolamine-induced working memory impairment in rats.
T26010 Quinacainol PK-10139,RP-54272,RP 54272,PK 10139,PK10139 Others
Quinacainol (RP 54272) is a new antiarrhythmic compound with class I antiarrhythmic effects in rats.

Compounds

Lerisetron
T8441
Synonym:
Target: 5-HT Receptor
RO 46-8443
T3474
Synonym:
Target: Endothelin Receptor
NS6180
T1752
Synonym:
Target: Potassium Channel
SBC-115076
T2626
Synonym: SBC115076
Target: Others, Serine/threonin kinase
SPHINX31
T5194
Synonym:
Target: Serine/threonin kinase
Zopolrestat
T35317
Synonym: CP 73850,CP73850,CP-73850,Zopolrestatum
Target: Reductase
Trandolapril
T5329
Synonym:
Target: Angiotensin-converting Enzyme (ACE)
Vardenafil hydrochloride
T8405
Synonym:
Target: PDE
Vardenafil
T0096
Synonym: Vivanza,Levitra,Vardenafil hydrochloride
Target: PDE
Metyrapone
T0293
Synonym: NSC-25265,Su-4885
Target: Others, P450, Dehydrogenase, Autophagy
BMY 7378 dihydrochloride
T3046
Synonym: BMY7378 HCl
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
VPC171
T29112
Synonym: VPC 171,VPC-171
Target: Adenosine Receptor
Vardenafil hydrochloride trihydrate
T4097
Synonym: Vardenafil HCl Trihydrate,BAY38-9456
Target: PDE
N,N'-Dicyclohexylurea
T23044
Synonym: DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582
Target: Epoxide Hydrolase
Ziprasidone hydrochloride
T0031L
Synonym: CP-88059 hydrochloride,CP-88059,Ziprasidone HCl
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Norepinephrine, Histamine Receptor
Vardenafil dihydrochloride
T4480
Synonym: Levitra,Vardenafil Hydrochloride
Target: PDE
JNJ-39220675
T27678
Synonym: JNJ39220675
Target:
ELB-139
T27252
Synonym: ELB139
Target:
RU 47213
T34435
Synonym: RU-47213,Itameline,RU47213
Target: Others
Quinacainol
T26010
Synonym: PK-10139,RP-54272,RP 54272,PK 10139,PK10139
Target: Others
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TargetMol