Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 263.00 | |
50 mg | In stock | $ 372.00 | |
100 mg | In stock | $ 549.00 | |
500 mg | In stock | $ 1,170.00 |
Description | RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition. |
Targets&IC50 | ET B:34-69 nM (IC50), ET A:6800 nM (IC50) |
Molecular Weight | 609.69 |
Formula | C31H35N3O8S |
CAS No. | 175556-12-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (90.21 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RO 46-8443 175556-12-4 GPCR/G Protein Endothelin Receptor Inhibitor RO 468443 Ro 46-8443 selective ETB normotensive RO 46 8443 inhibit hypertensive rats non-peptide inhibitor