Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 48.00 | |
200 mg | In stock | $ 79.00 | |
500 mg | In stock | $ 148.00 |
Description | Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME. |
Targets&IC50 | 11β-HSD1:30 μM(Ki) |
Synonyms | NSC-25265, Su-4885 |
Molecular Weight | 226.27 |
Formula | C14H14N2O |
CAS No. | 54-36-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 203.3 mM
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Metyrapone 54-36-4 Autophagy Metabolism Others P450 Dehydrogenase CYPs Cushing's syndrome emotion behavior Sprague-Dawley rats depression Inhibitor Su 4885 Su4885 11β-hydroxylase Cytochrome P450 inhibit NSC-25265 water maze Su-4885 NSC 25265 NSC25265 aldosterone Endogenous Metabolite inhibitor