neurotrophic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0084	Moclobemide	Ro111163	MAO , Monoamine Oxidase
	Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.		MAO , Monoamine Oxidase
TN2883	3',4'-Dimethoxyflavone		Others , PARP
	3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.		Others , PARP
T34114	Posatirelin	BRN 6006446,Posatirelinum,BRN-6006446,RGH-2202,BRN6006446	AChR
	Posatirelin (BRN6006446) is a synthetic peptide with modulatory activity and neurotrophic effects on monoaminergic and cholinergic systems for the study of vascular dementia.		AChR
T4779	4-Methylcatechol	p-Methylcatechol,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene	Others , Endogenous Metabolite
	4-Methylcatechol (3,4-Dihydroxytoluene) is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 2,3-dioxygenase. 4-Methylcatechol (3,4-Dihydroxytoluene) is known to induce t...		Others , Endogenous Metabolite
T4422	Edonerpic maleate	T-817MA,T-817 maleate	Beta Amyloid
	Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).		Beta Amyloid
TN4114	Gardenin A		ERK , LDL , MAPK , PKA , PKC
	Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.		ERK , LDL , MAPK , PKA , PKC
T13684	Equilin	7-Dehydroestrone	Calcium Channel
	Equilin (7-Dehydroestrone) is a neurotrophic estrogenic steroid with vasodilatory activity that increases monocyte-endothelial adhesion through NF-κB signalling.Equilin similarly relaxes mesenteric arterial resistance by...		Calcium Channel
T7568	LM22A-4		Trk receptor
	LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay)		Trk receptor
T77092	Nadecnemab	REGN-5069	Others
	Nadecnemab is an IGG4-κantibody targeting GFRA3, a receptor of the glial cell-derived neurotrophic factor family. Nadecnemab can be used for knee osteoarthritis and neurological disorders.		Others
T21470L	Davunetide acetate	Davunetide acetate(211439-12-2 Free base)	Beta Amyloid , Microtubule Associated
	Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicit...		Beta Amyloid , Microtubule Associated
T16430	Paliroden	SR 57667,SR 57667B	Others
	Paliroden is a non-peptide compound that can be taken orally and is used for supplementing neuro-nutrition. It stimulates the synthesis of endogenous neurotrophic factors and is employed in the research of neurodegenerat...		Others
T21244	NSI-189 Phosphate	NSI189 Phosphate,NSI 189 Phosphate	Others
	NSI-189 Phosphate is a novel neurogenic molecule with pleiotropic properties, including antidepressant, procognitive, synaptoplastic, and neurotrophic activities demonstrated in preclinical studies. Its antidepressant ac...		Others
T13587	BT18		Others
	BT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF). BT18 has an effect on RET receptor tyrosine kinase RetA and GDNF family receptor GFRα1 function.		Others
T10624	BT-13		c-RET
	BT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently of GFLs. BT-13 promotes neurite growth from sensory neurons in vitro.		c-RET
T37621	Ezeprogind disulfate		Beta Amyloid
	Ezeprogind disulfate is a neurotrophic inducer. Ezeprogind disulfate targets all causes of neurodegeneration including Abeta protein or tau protein. Ezeprogind disulfate can be used for the research of neurological disor...		Beta Amyloid
T8779	HBT1		GluR
	HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate...		GluR
T67955	Ensaculin	Anseculin
	Ensaculin (Anseculin), a novel benzopyrone partially substituted with piperazine, showed memory-enhancing effects in passive and conditioned avoidance paradigms in normal and artificially amnesic rodents. It showed neuro...
T33735	NS-1231
	NS-1231 exhibits neurotrophic-like effects in vitro and in vivo.
T29963	Americanol A
	Americanol A enhances choline acetyltransferase activity; has neurotrophic properties.
TP2444	Acth (7-16)NH2	ACTH - (7-16)-amide
	Acth (7-16)NH2 exhibits neurotrophic effects.