Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF). BT18 has an effect on RET receptor tyrosine kinase RetA and GDNF family receptor GFRα1 function.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 147.00 | |
25 mg | In stock | $ 269.00 | |
50 mg | In stock | $ 455.00 | |
100 mg | In stock | $ 690.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 113.00 |
Description | BT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF). BT18 has an effect on RET receptor tyrosine kinase RetA and GDNF family receptor GFRα1 function. |
In vitro | BT18 (1-50 μM; 90 minutes) activates AKT in a dose-dependent manner in MG87RET cell lines. BT18 (50 μM; 1-90 minutes) activates AKT and ERK1/2 in time-dependently in MG87RET cell lines. BT18 (5-50 μM; 15 minutes) appears to phosphorylate RET in the concentration of 50 μM both in GFP-transfected and in GFRD1-transfected cells [1]. |
Molecular Weight | 637.64 |
Formula | C30H31F4N3O6S |
CAS No. | 924811-53-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 98 mg/mL (153.69 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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BT18 924811-53-0 Others BT 18 Inhibitor inhibit BT-18 inhibitor