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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9723 | GluR6 antagonist-1 | Src | |
GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain. | |||
T23116 | Oxotremorine sesquifumarate | AChR | |
Oxotremorine sesquifumarate is a muscarinic agonist. | |||
T15052 | Dapansutrile | NOD-like Receptor (NLR) , NOD | |
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity. | |||
TP1856 | Colivelin | Beta Amyloid , STAT | |
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN). | |||
T9989 | AChE-IN-27 | Others | |
AChE-IN-27 is a small molecule used for high-throughput assays. | |||
T13320L | VU591 | Potassium Channel | |
1222810-74-3 | |||
T12421 | PF-04885614 | Sodium Channel | |
PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment. | |||
T4330 | CaCCinh-A01 | Chloride channel | |
CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM). | |||
T0776 | Phenothiazine | ENT 38 | Dopamine Receptor , Antibacterial , Antibiotic , Antifungal |
Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ)... | |||
T9694 | Emraclidine | CVL-231 | AChR |
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies. | |||
T9149 | 2BAct | 2B-Act,2B Act | PERK |
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response | |||
TQ0046 | Bavisant | JNJ-31001074 | Histamine Receptor |
Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD. | |||
T13320 | VU591 hydrochloride | Potassium Channel | |
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentr... | |||
T8944 | TTA-A2 | Calcium Channel | |
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ... | |||
T0082 | Domperidone | R33812 | Dopamine Receptor |
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger z... | |||
T1476 | Pramipexole | SND 919 | Dopamine Receptor |
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not... | |||
T8930 | CID44216842 | KUC103479N-02 | CDK , Ras |
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT... | |||
T1594 | Vecuronium bromide | ORG NC 45 | AChR |
Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity. | |||
T4074 | GSK-872 | GSK872,GSK'872,GSK2399872A | RIP kinase |
GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM). | |||
T6950 | PNU-120596 | NSC 216666 | AChR |
PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM. |