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Search Results for " neurological "

20

Compounds

Cat No. Product Name Synonyms Targets
T9723 GluR6 antagonist-1 Src
GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.
T23116 Oxotremorine sesquifumarate AChR
Oxotremorine sesquifumarate is a muscarinic agonist.
T15052 Dapansutrile NOD-like Receptor (NLR) , NOD
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
TP1856 Colivelin Beta Amyloid , STAT
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).
T9989 AChE-IN-27 Others
AChE-IN-27 is a small molecule used for high-throughput assays.
T13320L VU591 Potassium Channel
1222810-74-3
T12421 PF-04885614 Sodium Channel
PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.
T4330 CaCCinh-A01 Chloride channel
CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).
T0776 Phenothiazine ENT 38 Dopamine Receptor , Antibacterial , Antibiotic , Antifungal
Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ)...
T9694 Emraclidine CVL-231 AChR
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.
T9149 2BAct 2B-Act,2B Act PERK
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response
TQ0046 Bavisant JNJ-31001074 Histamine Receptor
Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.
T13320 VU591 hydrochloride Potassium Channel
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentr...
T8944 TTA-A2 Calcium Channel
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ...
T0082 Domperidone R33812 Dopamine Receptor
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger z...
T1476 Pramipexole SND 919 Dopamine Receptor
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not...
T8930 CID44216842 KUC103479N-02 CDK , Ras
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT...
T1594 Vecuronium bromide ORG NC 45 AChR
Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity.
T4074 GSK-872 GSK872,GSK'872,GSK2399872A RIP kinase
GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
T6950 PNU-120596 NSC 216666 AChR
PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.
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