Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 137.00 | |
25 mg | In stock | $ 283.00 | |
50 mg | In stock | $ 452.00 | |
100 mg | In stock | $ 665.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 89.00 |
Description | CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe. |
Targets&IC50 | CDC42 (WT, GDP binding assay):0.3 μM (EC50), CDC42 (Q61L mutant, GDP binding assay):0.5 μM (EC50), CDC42 (Q61L mutant, GDP binding assay):1.2 μM (EC50), CDC42 (WT, GTP binding assay):1.0 μM (EC50) |
Synonyms | KUC103479N-02 |
Molecular Weight | 486.38 |
Formula | C22H20BrN3O3S |
CAS No. | 1222513-26-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (514.00 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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CID44216842 1222513-26-9 Cell Cycle/Checkpoint GPCR/G Protein MAPK Ras CDK diseases CID 44216842 neutrophils ovarian disorders Cdc42 fibroblasts breast CID-44216842 hepatitis C retardation Inhibitor KUC103479N-02 cancer kidney epithelia mental inhibit immune virus neurological inhibitor