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Colivelin

🥰Excellent
Catalog No. TP1856Cas No. 867021-83-8

Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).

Colivelin
Other Forms of Colivelin:
Colivelin TFA (867021-83-8 free base)TP12782803948-60-7
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Colivelin

🥰Excellent
Purity: 96.56%
Catalog No. TP1856Cas No. 867021-83-8
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).
Pack SizePriceAvailabilityQuantity
500 μg$156 In Stock
1 mg$237 In Stock
5 mg$592 In Stock
10 mg$973 In Stock
25 mg$1,430 In Stock
50 mg$1,930 In Stock
100 mg$2,630 In Stock
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Purity:96.56%
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Product Introduction

Bioactivity
Description
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).
Chemical Properties
Molecular Weight2645.1
FormulaC119H206N32O35
Cas No.867021-83-8
SmilesC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CO)=O)[C@H](CC)C)(=O)N1[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(O)=O)CCC3)CC(C)C)=O)CC(O)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CO)=O)C)=O)=O)C)=O)CCC2)C)=O)CCC1
Relative Density.1.42 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (Insoluble or slightly soluble)
DMSO: 50 mg/mL (18.90 mM), Sonication is recommended.
In Vivo Formulation
PBS: < 1 mg/mL (Insoluble or slightly soluble)
5% DMSO+40% PEG300+5% Tween 80+50% Saline: 1 mg/mL (0.38 mM), In vivo: Please add co-solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.3781 mL1.8903 mL3.7806 mL18.9029 mL
5 mM0.0756 mL0.3781 mL0.7561 mL3.7806 mL
10 mM0.0378 mL0.1890 mL0.3781 mL1.8903 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

β-amyloid peptideβAmyloidβ AmyloidSTAT3STATNeuroprotectantneurologicalischemicinjuryInhibitorinhibitdiseaseColivelinbrainBetaAmyloidBeta AmyloidbAmyloidb AmyloidAmyloid-βalzheimerAbeta
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