kinase-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16987	TAO Kinase inhibitor 1		Others , MAPK
	TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectiv...		Others , MAPK
T12721	Rho-Kinase-IN-1		ROCK
	Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation dise...		ROCK
T9564	IRE1α kinase-IN-1		IRE1
	IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosph...		IRE1
T67755	Protein kinase G inhibitor-1		PKA
	Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.		PKA
T6335	Tie2 kinase inhibitor 1	Tie2 kinase inhibitor	Tie-2
	Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38.		Tie-2
T11184	EML4-ALK kinase inhibitor 1	EML4 ALK kinase inhibitor 1,EML4-ALK kinase inhibitor 1	ALK
	EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.		ALK
T5466	Tyrosine kinase-IN-1		VEGFR , FGFR , FLT , PDGFR
	Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）		VEGFR , FGFR , FLT , PDGFR
T6409	ALK kinase inhibitor-1	SAR348830	Others
	SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.		Others
T4191	Multi-kinase inhibitor 1	Multi-kinase inhibitor I	Others , Bcr-Abl , PDGFR , c-Kit
	Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.		Others , Bcr-Abl , PDGFR , c-Kit
T9229	Pim-1/2 kinase inhibitor 1		Pim
	Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim ...		Pim
T4692	Protein kinase inhibitors 1 hydrochlorid	Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base))	Others
	Protein kinase inhibitors 1 hydrochlorid (Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base))) is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.		Others
T60295	Casein kinase 1δ-IN-1	WAY-643895	Casein Kinase
	Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ. Casein kinase 1δ-IN-1 can be used in the study of neurodegenerative diseases such as Alzheimer's disease.		Casein Kinase
T83627	Pim-1 kinase inhibitor 8		Pim , PKC
	Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound ...		Pim , PKC
T39178	Tyrosine Kinase Peptide 1
	Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay.
T39860	Protein kinase inhibitors 1 hydrochloride
	Protein Kinase Inhibitors 1 Hydrochloride effectively inhibits HIPK2, demonstrating high potency with IC50 values of 136 nM for HIPK1 and 74 nM for HIPK2, alongside a dissociation constant (Kd) of 9.5 nM for HIPK2.
T4636	Protein kinase inhibitors 1		Others , DYRK
	Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.		Others , DYRK
T60688	MKI-1	MASTL Kinase Inhibitor-1	Others
	MKI-1 (MASTL Kinase Inhibitor-1) is an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like, IC50= 9.9 μM). MKI-1 exerts radiosensitizer and antitumor activities through PP2A activation in breast cance...		Others
T11761	Tarlox-TKI	Kinase inhibitor-1	EGFR
	Tarlox-TKI (Kinase inhibitor-1) is a pan-ErbB inhibitor, the active ingredient of Tarloxotinib, with antitumor activity.Tarlox-TKI inhibits NRG1 and suppresses HER2 mutants.		EGFR
T12725	RIP1 kinase inhibitor 1		Others
	RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04.		Others
T12396	PDGFRα kinase inhibitor 1		PDGFR
	PDGFRα kinase inhibitor 1 is a highly selective inhibitor of type II PDGFRα kinase (PDGFRα and PDGFRβ with IC50s of 132 nM and 6115 nM , respectively).		PDGFR