Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 1,200.00 | |
50 mg | 10-14 weeks | $ 1,570.00 | |
100 mg | 10-14 weeks | $ 2,390.00 |
Description | RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04. |
Targets&IC50 | RIP1 kinase:pki:9.04 |
In vitro | RIP1 kinase inhibitor 1 strongly suppresses necroptotic cell death and phosphorylation of MLKL(pMLKL) in human colorectal adenocarcinoma HT-29 cells with IC50 of 2 nM and 1.3 nM for nectoptosis and pMLKL) as well as mouse L-cells NCTC 929 (nectoptosis, IC50=15 nM; pMLKL, IC50=2.7 nM). |
Molecular Weight | 461.9 |
Formula | C24H20ClN5O3 |
CAS No. | 2095515-38-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RIP1 kinase inhibitor 1 2095515-38-9 Others RIP-1 kinase inhibitor 1 inhibitor inhibit