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Search Results for " kallikrein 1 "

Targets

13

Compounds

1742

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T40312 Plasma kallikrein-IN-1 Others
Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.
T63579 Kallikrein-IN-1 Others
Kallikrein-IN-1 (Formula A) is an inhibitor of the kinin-releasing enzyme Kallikrein.
T63796 Kallikrein-IN-2 Others
Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.
T61403 Plasma kallikrein-IN-3 Others
Plasma kallikrein-IN-3, a potent inhibitor ( IC 50 : 0.15 μM) of plasma kallikrein, finds application in research related to hereditary angioedema, diabetic macular edema, and diabetic retinopathy [1].
T80271 Irucalantide
Irucalantide is a kallikrein inhibitor [1].
T73611 Kallikrein Others
Kallikrein is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides , respectively [1] .
T77999 KKI-5 TFA
KKI-5 (TFA), a specific tissue kallikrein inhibitor, has been shown to inhibit breast cancer cell invasion [1].
T80095 D-Pro-Phe-Arg-Chloromethylketone Factor Xa
D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammation [1].
T35869 Berotralstat Others
Berotralstat (BCX7353) is a second-generation, synthetic, and orally active plasma kallikrein inhibitor with low toxicity. It is highly specific and effectively used in the research of hereditary angioedema (HAE) attacks...
T82510 Ecallantide TFA DX-88 TFA Others
Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of acute angioedema attacks [1].
T76710 Lanadelumab
Lanadelumab (SHP643), a humanized IgG1 monoclonal antibody, targets plasma kallikrein (pKal) with a K i value of 0.12 nM, effectively inhibiting both its free form and its interaction with high molecular weight kininogen...
T78572 Ecallantide DX-88 Others
Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin. It is utilized to prevent acute episodes of angioedema [1].
T76248 Tutuilamide A
Tutuilamide A, a potent inhibitor of porcine pancreatic elastase (PPE) with an IC50 of 1.2 nM, also effectively inhibits human neutrophil elastase (HNE; IC50=0.73 nM) and kallikrein 7 (KLK7; IC50=5.0 nM) [1].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00866 Kallikrein 1/KLK1 Protein, Human, Recombinant (His) Human HEK293 Cells
Kallikrein 1/KLK1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is A0A1R3UCD2.
TMPJ-00475 Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His) Human HEK293 Cells
Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The f...
TMPY-04032 Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.3 kDa and the accession number is P15947.
TMPK-00766 KLKB1 Protein, Human, Recombinant (His) Human HEK293 Cells
Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze th...
TMPJ-00891 Kallikrein 2/KLK2 Protein, Human, Recombinant (His) Human HEK293 Cells
Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave ...
TMPY-01900 Kallikrein 4/KLK4 Protein, Human, Recombinant (His) Human HEK293 Cells
Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein ...
TMPK-00857 KLKB1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze th...
TMPK-00525 KLKB1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze th...
TMPJ-00468 KLK10 Protein, Human, Recombinant (His) Human HEK293 Cells
KLK10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 34 KDa and the accession number is AAH02710.1.
TMPY-05289 Kallikrein 15/KLK15 Protein, Human, Recombinant (His) Human HEK293 Cells
Kallikrein 15/KLK15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.8 kDa and the accession number is Q9H2R5-1.
TMPY-00491 Kallikrein 15/KLK15 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Kallikrein 15/KLK15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.1 kDa and the accession number is Q9H2R5-1.
TMPK-01158 Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulat...
TMPJ-00931 Serpin A4 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&...
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-02335 OSMR Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
OSMR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 83.7 kDa and the accession number is O70458-1.
TMPY-02112 FGFR4 Protein, Human, Recombinant (His) Human HEK293 Cells
FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1.
TMPY-01920 BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) Human HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1.
TMPY-01053 Prolactin Receptor Protein, Human, Recombinant (His) Human HEK293 Cells
Prolactin Receptor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P16471-1.
TMPY-01349 ICAM-1/CD54 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1.
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S) Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-00742 EGFR Protein, Human, Recombinant (His) Human HEK293 Cells
EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-02603 STAT6 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPY-01003 TCN2 Protein, Human, Recombinant (His) Human HEK293 Cells
TCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P20062-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-01968 CD32A Protein, Human, Recombinant (167 His, His) Human HEK293 Cells
CD32A Protein, Human, Recombinant (167 His, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P12318-1.
TMPY-01395 CTHRC1 Protein, Human, Recombinant (His) Human HEK293 Cells
CTHRC1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.5 kDa and the accession number is Q96CG8-1.
TMPY-01389 HER3/ERBB3 Protein, Human, Recombinant (His) Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
TMPY-01813 ACRV1 Protein, Human, Recombinant (His) Human HEK293 Cells
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the a...
TMPY-02700 BCL2 Protein, Human, Recombinant (His) Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPY-05840 IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.56 kDa and the accession number is P59822-1.
TMPY-04104 LIF Protein, Human, Recombinant Human HEK293 Cells
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-00925 SOST Protein, Human, Recombinant (His) Human HEK293 Cells
SOST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPY-02062 SULT1A1 Protein, Human, Recombinant (His) Human E. coli
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroid...
TMPY-03782 Albumin Protein, Human, Recombinant Human P. pastoris (Yeast)
Albumin Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 66.4 kDa and the accession number is P02768-1.
TMPY-00843 IL-25/IL17E Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-25/IL17E Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45 kDa and the accession number is Q9H293-1.
TMPY-04153 RNF43 Protein, Human, Recombinant (His) Human HEK293 Cells
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr...
TMPY-01209 IL-7R alpha/CD127 Protein, Human, Recombinant (His) Human HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
TMPY-05566 Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) is expressed in HEK293 mammalian cells with His tag. The accession number is P20273-1.
TMPY-01137 HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
TMPY-05593 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.4 kDa and the accession number is Q9NPH3-1.
TMPY-00835 IGFBP-3 Protein, Human, Recombinant (His) Human HEK293 Cells
IGFBP-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is P17936-1.
TMPY-04824 CTLA-4 Protein, Human, Recombinant Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1.
TMPY-01062 EGF Protein, Human, Recombinant (hFc) Human HEK293 Cells
EGF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33 kDa and the accession number is P01133-1.
TMPY-00686 Complement C2 Protein, Human, Recombinant (His) Human HEK293 Cells
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P06681-1.
TMPY-01934 IL-21R Protein, Human, Recombinant (His) Human HEK293 Cells
IL-21R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q9HBE5-1.
TMPY-01145 NKp30/NCR3 Protein, Human, Recombinant (His) Human HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.4 kDa and the accession number is O14931-1.
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Kallikrein 1/KLK1 Protein, Human, Recombinant (His)
TMPY-00866
Species: Human
Expression System: HEK293 Cells
Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)
TMPJ-00475
Species: Human
Expression System: HEK293 Cells
Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His)
TMPY-04032
Species: Mouse
Expression System: HEK293 Cells
KLKB1 Protein, Human, Recombinant (His)
TMPK-00766
Species: Human
Expression System: HEK293 Cells
Kallikrein 2/KLK2 Protein, Human, Recombinant (His)
TMPJ-00891
Species: Human
Expression System: HEK293 Cells
Kallikrein 4/KLK4 Protein, Human, Recombinant (His)
TMPY-01900
Species: Human
Expression System: HEK293 Cells
KLKB1 Protein, Mouse, Recombinant (His)
TMPK-00857
Species: Mouse
Expression System: HEK293 Cells
KLKB1 Protein, Cynomolgus, Recombinant (His)
TMPK-00525
Species: Cynomolgus
Expression System: HEK293 Cells
KLK10 Protein, Human, Recombinant (His)
TMPJ-00468
Species: Human
Expression System: HEK293 Cells
Kallikrein 15/KLK15 Protein, Human, Recombinant (His)
TMPY-05289
Species: Human
Expression System: HEK293 Cells
Kallikrein 15/KLK15 Protein, Human, Recombinant (hFc)
TMPY-00491
Species: Human
Expression System: HEK293 Cells
Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His)
TMPK-01158
Species: Mouse
Expression System: HEK293 Cells
Serpin A4 Protein, Human, Recombinant (His)
TMPJ-00931
Species: Human
Expression System: HEK293 Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293 Cells
OSMR Protein, Mouse, Recombinant (His)
TMPY-02335
Species: Mouse
Expression System: HEK293 Cells
FGFR4 Protein, Human, Recombinant (His)
TMPY-02112
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
TMPY-01920
Species: Human
Expression System: HEK293 Cells
Prolactin Receptor Protein, Human, Recombinant (His)
TMPY-01053
Species: Human
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Mouse, Recombinant (His)
TMPY-01349
Species: Mouse
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
TMPY-00820
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (His)
TMPY-00742
Species: Human
Expression System: HEK293 Cells
STAT6 Protein, Human, Recombinant (His)
TMPY-02603
Species: Human
Expression System: Baculovirus Insect Cells
TCN2 Protein, Human, Recombinant (His)
TMPY-01003
Species: Human
Expression System: HEK293 Cells
FLT3 Ligand Protein, Human, Recombinant
TMPY-06873
Species: Human
Expression System: E. coli
CD32A Protein, Human, Recombinant (167 His, His)
TMPY-01968
Species: Human
Expression System: HEK293 Cells
CTHRC1 Protein, Human, Recombinant (His)
TMPY-01395
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His)
TMPY-01389
Species: Human
Expression System: HEK293 Cells
ACRV1 Protein, Human, Recombinant (His)
TMPY-01813
Species: Human
Expression System: HEK293 Cells
BCL2 Protein, Human, Recombinant (His)
TMPY-02700
Species: Human
Expression System: E. coli
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)
TMPY-05840
Species: Cynomolgus
Expression System: HEK293 Cells
LIF Protein, Human, Recombinant
TMPY-04104
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant
TMPY-04939
Species: Human
Expression System: HEK293 Cells
SOST Protein, Human, Recombinant (His)
TMPY-00925
Species: Human
Expression System: HEK293 Cells
SULT1A1 Protein, Human, Recombinant (His)
TMPY-02062
Species: Human
Expression System: E. coli
Albumin Protein, Human, Recombinant
TMPY-03782
Species: Human
Expression System: P. pastoris (Yeast)
IL-25/IL17E Protein, Human, Recombinant (hFc)
TMPY-00843
Species: Human
Expression System: HEK293 Cells
RNF43 Protein, Human, Recombinant (His)
TMPY-04153
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His)
TMPY-01209
Species: Human
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
TMPY-05566
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
TMPY-01137
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05593
Species: Human
Expression System: HEK293 Cells
IGFBP-3 Protein, Human, Recombinant (His)
TMPY-00835
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant
TMPY-04824
Species: Human
Expression System: HEK293 Cells
EGF Protein, Human, Recombinant (hFc)
TMPY-01062
Species: Human
Expression System: HEK293 Cells
Complement C2 Protein, Human, Recombinant (His)
TMPY-00686
Species: Human
Expression System: HEK293 Cells
IL-21R Protein, Human, Recombinant (His)
TMPY-01934
Species: Human
Expression System: HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (His)
TMPY-01145
Species: Human
Expression System: HEK293 Cells
TargetMol