immunomodulator — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1846	Y-320	Y320	IL Receptor , Lipase , Interleukin
	Y-320 is a new phenylpyrazoleanilide immunomodulator.		IL Receptor , Lipase , Interleukin
T21694	(R)-Lisofylline	(R)-Lisophylline	STAT
	(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM). (R)-Lisofylline interrupts IL-12 signaling-mediated STAT4 activation and can be used in studies about the treat...		STAT
T6561	Laquinimod	LAQ,ABR-215062	Apoptosis , Others , NF-κB
	Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.		Apoptosis , Others , NF-κB
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
T16913	Sotirimod	R850,S-30594	Virus Protease
	Sotirimod（R850） is a novel immunomodulator with antitumor and antiviral activity for the study of actinic keratoses.		Virus Protease
T4640	Parimifasor	LYC30937	Others
	Parimifasor (LYC30937) is an immunomodulator, with anti-inflammatory activity.		Others
T7203	Oglufanide	L-Glutamyl-L-tryptophan,H-Glu-Trp-OH	VEGFR , HCV Protease , Endogenous Metabolite
	Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).		VEGFR , HCV Protease , Endogenous Metabolite
T25705	Imupedone	LF1695,LF-1695,LF 1695	Others
	Imupedone (LF 1695) is a synthetic immunomodulator that modulates T lymphocytes and macrophages, induces T-cell differentiation of bone marrow precursor cells, and increases the proliferative response of lymphocytes to m...		Others
T31648	Epetirimod	S 30563,S-30563,S30563	Antiviral
	Epetirimod (S-30563) is a small molecule immunomodulator with antitumor and anti-infective activity for the study of papillomavirus infections.		Antiviral
T5043	Lentinan		Others
	Lentinan, isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.		Others
T18819	Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride		Others , Ligand for E3 Ligase
	Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker. Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride can be used as an immunomodulator for the treatment of cancer.		Others , Ligand for E3 Ligase
T14846	Bz 423	BZ48	Apoptosis , BCL
	Bz 423 is a potent immunomodulator that induces apoptosis by activating Bax and Bak to induce mitochondrial outer membrane permeabilization and cytochrome c release.Bz 423 shows partial activity in a mouse model of lupus...		Apoptosis , BCL
T2384	Pomalidomide	CC-4047	Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
	Pomalidomide (CC-4047) inhibits TNF-α release in LPS stimulated human PBMCs (IC50: 13 nM). It is an anti-angiogenic agent and an immunomodulator.		Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
T6761	Ossirene	AS101	IL Receptor , Caspase , Interleukin
	Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.		IL Receptor , Caspase , Interleukin
T2598	Thymopentin	TP5	Estrogen/progestogen Receptor , Endogenous Metabolite
	Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. Thymopentin (TP5) is an immunomodulator which has been studied for possibl...		Estrogen/progestogen Receptor , Endogenous Metabolite
T68043	Ciamexon	Ciamexone,BM 41332,BM41332,BM-41332	Others
	Ciamexon (Ciamexone) is a novel immunomodulator that has shown promising results in experimental models of autoimmune disease with little demonstrated cytotoxicity.Ciamexon can be used to study endocrine ophthalmopathies...		Others
T34249	Rabeximod	ROB-803	TLR
	Rabeximod is a potent immunomodulator that reduces the severity of autoimmune diseases in rat models. Rabeximod inhibits arthritis in a time-dependent manner by stimulating TLR2 and TLR4 downstream to block the activatio...		TLR
T13666	Dupilumab	REGN-668,SAR-231893	IL Receptor
	Dupilumab (REGN-668) is a systemic immunomodulator for AD. Dupilumab is a fully human monoclonal antibody against the alpha subunit of the interleukin-4 receptor, which inhibits downstream signaling of IL-4 and IL-13 and...		IL Receptor
T3655	BMS-1	PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1	Apoptosis , PD-1/PD-L1
	BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene ...		Apoptosis , PD-1/PD-L1
T28087	Mosedipimod
	Mosedipimod is an immunomodulator.