Shopping Cart
- Remove All
- Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $39 | In Stock | |
2 mg | $57 | In Stock | |
5 mg | $89 | In Stock | |
10 mg | $126 | In Stock | |
25 mg | $236 | In Stock | |
50 mg | $417 | In Stock | |
100 mg | $619 | In Stock | |
1 mL x 10 mM (in DMSO) | $98 | In Stock |
Description | Y-320 is a new phenylpyrazoleanilide immunomodulator. |
Targets&IC50 | IL-17 production:20-60 nM |
In vitro | Y-320 can inhibit the production of IFN-γ and TNF-α in mouse CD4 T cells stimulated by IL-15, CXCL12, and anti-CD3 monoclonal antibody. |
In vivo | Y-320 (administered orally at doses of 0.3-3 mg/kg) enhances the improvement of collagen-induced arthritis (CIA) in mice, concurrently reducing the expression levels of IL-17 mRNA within arthritic joints. Additionally, it has demonstrated therapeutic efficacy for CIA in crab-eating macaques. |
Alias | Y320 |
Molecular Weight | 505.01 |
Formula | C27H29ClN6O2 |
Cas No. | 288250-47-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | Ethanol: < 1 mg/mL (insoluble or slightly soluble) H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 9 mg/mL (17.8 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.