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Y-320

Y-320
Y-320 is a new phenylpyrazoleanilide immunomodulator.
Catalog No. T1846Cas No. 288250-47-5
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Purity:99.64%
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Y-320

Catalog No. T1846Cas No. 288250-47-5

Y-320 is a new phenylpyrazoleanilide immunomodulator.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
2 mg$57In Stock
5 mg$89In Stock
10 mg$126In Stock
25 mg$236In Stock
50 mg$417In Stock
100 mg$619In Stock
1 mL x 10 mM (in DMSO)$98In Stock
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Product Introduction

Bioactivity
Description
Y-320 is a new phenylpyrazoleanilide immunomodulator.
Targets&IC50
IL-17 production:20-60 nM
In vitro
Y-320 can inhibit the production of IFN-γ and TNF-α in mouse CD4 T cells stimulated by IL-15, CXCL12, and anti-CD3 monoclonal antibody.
In vivo
Y-320 (administered orally at doses of 0.3-3 mg/kg) enhances the improvement of collagen-induced arthritis (CIA) in mice, concurrently reducing the expression levels of IL-17 mRNA within arthritic joints. Additionally, it has demonstrated therapeutic efficacy for CIA in crab-eating macaques.
AliasY320
Chemical Properties
Molecular Weight505.01
FormulaC27H29ClN6O2
Cas No.288250-47-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 9 mg/mL (17.8 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9802 mL9.9008 mL19.8016 mL99.0079 mL
5 mM0.3960 mL1.9802 mL3.9603 mL19.8016 mL
10 mM0.1980 mL0.9901 mL1.9802 mL9.9008 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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