hypolipidemic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14933	Cetaben		Others
	Cetaben is a PPARα-independent peroxisome proliferator and is a non-fibrate hypolipidemic drug. It potent reduces the concentration of cholesterol and triglycerides.		Others
T3941	Choline Fenofibrate	Trilipix,ABT-335	P450 , COX , PPAR
	Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.		P450 , COX , PPAR
T5123	Pirozadil		Others
	Pirozadil shows hypolipidemic activity.		Others
T15471	Hepronicate	Megrin	Others
	Hepronicate（Megrin） is a small molecule compound with hypolipidemic and vasodilatory activity.		Others
T3S0175	Gardenia yellow	alpha-Crocin,Crocin I,Crocine	Sirtuin
	Gardenia yellow (Crocin I) has anti atherosclerosis and hypolipidemic effects.		Sirtuin
T30506	BMS-212122	UNII-0Z473OO6GB,BMS212122,BMS 212122	CETP
	BMS-212122 (UNII-0Z473OO6GB) is a potent inhibitor of microsomal triglyceride transfer protein (MTP) and has shown hypolipidemic effects in animal studies.BMS-212122 significantly reduced lipid content and monocyte-deriv...		CETP
T19864	Xenalipin	BW 207U	Others
	Xenalipin (BW 207U) has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.		Others
T5311	Crocin (Gardenia Fruits Extract)		Others
	Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.). Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidemic effects.		Others
T2756	Swertiamarin	Swertiamaroside	Others
	Swertiamarin (Swertiamaroside) is a common secoiridoid found among the members of Gentianaceae with anti-inflammatory, anticancer, hypoglycemic and hypolipidemic activities.		Others
T31083	CP-868388 free base	CP868388,CP 868388,(-)-CP-868388,UNII-999KY5ZIGB,CP-868388	PPAR
	CP-868388 free base (CP-868388) is an orally active, potent and selective PPARα agonist with hypolipidemic and anti-inflammatory activity for the study of dyslipidemia.		PPAR
T5690	7,4'-Di-O-methylapigenin	4',7-DIMETHOXY-5-HYDROXYFLAVONE	Amylase
	7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines.		Amylase
T27832	Lifibrol	U 83860,K-12148,K-12.148,U-83860,K12148	Lipid
	Lifibrol (U-83860) is an inhibitor of cholesterol synthesis.Lifibrol has anticholesterol and hypolipidemic properties and promotes the conversion of LDL Apo B-100 in patients with hypercholesterolemia and mixed hyperlipi...		Lipid
T5707	3-O-Methylgalangin	3-Methylgalangin,GALANGIN-3-METHYLETHER	Antibacterial
	3-O-Methylgalangin (GALANGIN-3-METHYLETHER) has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the inhibition of pancr...		Antibacterial
T2840	Phloracetophenone	2,4,6-trihydroxyacetophenone,1-(2,4,6-Trihydroxyphenyl)ethanone	Others , P450 , Antibacterial , Antibiotic
	Phloracetophenone (1-(2,4,6-Trihydroxyphenyl)ethanone) has antiobesity and hypolipidemic effects, may be partly mediated by delaying the intestinal absorption of dietary fat by inhibiting pancreatic lipase activity.		Others , P450 , Antibacterial , Antibiotic
T5431	[10]-Shogaol	10-Shogaol	Antioxidant , COX
	[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.		Antioxidant , COX
T1162	Acipimox	Olbemox,K-9321	Others
	Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.		Others
T0687	Simvastatin	MK-0733,MK 733	Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
	Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc...
T3884	Neoandrographolide	Neoandrographiside	NOS , COX
	Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iN...		NOS , COX
T8189	Dihydroberberine		Potassium Channel , HSP , HER
	Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti...		Potassium Channel , HSP , HER
T67974	Berberine ursodeoxycholate	HTD1801,BUDCA
	Berberine ursodeoxycholate (HTD1801) is an orally effective hypolipidemic agent, an ionic salt of Berberine and Ursodeoxycholic acid.Berberine ursodeoxycholate has a wide range of metabolic activity and significantly red...