Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 47.00 | |
10 mg | In stock | $ 80.00 | |
25 mg | In stock | $ 163.00 | |
50 mg | In stock | $ 258.00 | |
100 mg | In stock | $ 383.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 52.00 |
Description | Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity. |
Kinase Assay | Cells are harvested, washed, and lysed in NP-40 lysis buffer (50 mM Tris-HCl [pH 7.5], 150 mM NaCl, 0.5% NP-40). Total cell protein is quantified using the Bradford assay and 1-mg/mL protein aliquots are made. Ten microliters of total cell protein is mixed with 290 μL of substrate solution (0.1 mg/mL dithiothreitol [DTT], 0.1 mg/mL albumin, and 1 mM alanine-β-naphthylamide). Fluorometric measurements (340 nm excitation, 400 nm emission) are made after 15 and 30 min. The slope of the line between the 15- and 30-min measurements is used to represent aminopeptidase activity. Total cell protein is preincubated with bestatin, amastatin, puromycin, EDTA, and/or ZnCl2 for 20 min before the fluorometric aminopeptidase assay. |
Synonyms | Trilipix, ABT-335 |
Molecular Weight | 421.91 |
Formula | C22H28ClNO5 |
CAS No. | 856676-23-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6.2 mg/mL, Sonification and heating are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Choline Fenofibrate 856676-23-8 DNA Damage/DNA Repair Immunology/Inflammation Metabolism Neuroscience P450 COX PPAR hyperlipidemia Trilipix Cyclooxygenase ABT-335 Fenofibric ABT335 hypolipidemic anti-inflammatory Inhibitor ABT 335 acid Peroxisome proliferator-activated receptors inhibit inhibitor