fibers — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7144	BTS	N-Tosylbenzylamine,N-Benzyl-p-toluenesulfonamide	ATPase , Myosin
	BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .		ATPase , Myosin
T20386	Caprolactam		Others
	Caprolactam is a natural product used in the manufacture of synthetic fibers of the polyamide type.		Others
T23401	Strontium chloride		Others , CaSR
	Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.		Others , CaSR
T0924	Benzocaine		Others , MRP , Sodium Channel
	Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.		Others , MRP , Sodium Channel
T7218	Endomorphin 2		Opioid Receptor
	Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers f...		Opioid Receptor
T15716	Lasalocid sodium	Ionophore X-537A sodium,Antibiotic X-537A sodium,Lasalocid-A sodium	Antibacterial , Antibiotic , Autophagy
	Lasalocid sodium (Lasalocid-A sodium) is a cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. Lasalocid sodium is used as a co...		Antibacterial , Antibiotic , Autophagy
T8195	Lotusine		Others
	Lotusine is a pure alkaloid extracted from the Nelumbo nucifera Gaertn. It shows effects on the action potentials in the myocardium and slow inward current in cardiac Purkinje fibers.		Others
TD0098	Direct Red 80	Sirius Red,Sirius Red F 3BA,C.I. direct red 80	Others
	Direct Red 80 (Sirius Red) is a tetra azo dye. It can be used to detect amyloid and can magnify the usual birefringence of collagen fibers in tissue sections.		Others
T30249	AZD 7009	AZD-7009,AZD7009	Sodium Channel
	AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM. AZD 7009 inhibited late sodium current in isolated rabbit atrial and ventricular myocytes, an...		Sodium Channel
T0866	Propafenone	Rythmol,Propafenonum	Potassium Channel , MRP , Sodium Channel
	Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity....		Potassium Channel , MRP , Sodium Channel
TP1325L	Gastrin-Releasing Peptide, human(TFA)		Others
	Gastrin-Releasing Peptide, human(TFA) is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innerva...		Others
TN1216	2-O-Acetyl-20-hydroxyecdysone	20-Hydroxyeedysone 2-acetate	Beta Amyloid , Others
	2-O-Acetyl-20-hydroxyecdysone is an ecdysone present in insects and terrestrial plants. 2-O-Acetyl-20-hydroxyecdysone inhibits amyloid-β42-induced cytotoxicity and is able to reduce the formation of Aβ oligomers by promo...		Beta Amyloid , Others
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T1046	Mexiletine hydrochloride	KOE-1173 (hydrochloride),Mexiletine HCl,KO1173	AhR , Sodium Channel
	Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myoca...		AhR , Sodium Channel
T0210L	Tamsulosin	LY253351 free base,HSDB7744,(R)-(-)-YM12617 free base,Harnal-D,Flowmax,HSDB 7744,HSDB-7744	Adrenergic Receptor
	Tamsulosin ((R)-(-)-YM12617 free base) is an alpha1A adrenergic receptor antagonist for the symptomatic treatment of benign prostatic hyperplasia (BPH). Tamsulosin is used to treat difficulty urinating, a common symptom ...		Adrenergic Receptor
T77577	SLU-PP-332		Estrogen/progestogen Receptor
	SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ with EC50 values of 98, 230, and 430 nM, respectively.SLUPP-332 enhances mitochondrial function and cellula...		Estrogen/progestogen Receptor
T2163	Dihydrocapsaicin	CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide	Others , TRP/TRPV Channel
	Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...		Others , TRP/TRPV Channel
T32724	LF 14	LF14,LF-14
	LF 14 affects mammalian non-myelinated nerve fibers.
T20032	CI Direct Brown 2	Airedale Brown MD,Brown M,NSC 74701,Direct Brown 2,NSC-74701,NSC74701
	CI Direct Brown 2 is a direct dye. It is soluble in water and ionizable to form colored anions. It also can directly dye cellulose fibers or protein fibers.
T61215	Alinidine hydrobromide
	Alinidine hydrobromide, a specific bradycardic agent, diminishes the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers [1].