drug-related — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3971	CASIN	Pirl1-related Compound 2	CDK , STAT , Ras
	CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).		CDK , STAT , Ras
T8702	SKF-83566		Dopamine Receptor , 5-HT Receptor , AChR
	SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM		Dopamine Receptor , 5-HT Receptor , AChR
TP1215	Abaloparatide TFA	BA 058 TFA,Abaloparatide TFA (247062-33-5 free base),BIM 44058 TFA	Others
	Abaloparatide TFA (BIM 44058 TFA) is a parathyroid hormone-related protein (PTHrP) analog drug used to treat osteoporosis like the related drug teriparatide.		Others
T4269	Buparvaquone	Butalex,BW 720C	Antibiotic , Parasite
	Buparvaquone (BW 720C) is a hydroxynaphthoquinone antiprotozoal drug related to atovaquone and parvaquone.		Antibiotic , Parasite
T76864	Enapotamab		TAM Receptor
	Enapotamab is an AXL/UFO-related antibody that can be used to synthesize antibody-drug couplings (Enapotamab Vedotin).		TAM Receptor
T1734	Rabeprazole Sulfide	Rabeprazole Related Compound E	Proton pump , Antibacterial
	Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.		Proton pump , Antibacterial
T4688	Pipequaline hydrochloride	PK-8165 hydrochloride	GABA Receptor
	Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely re...		GABA Receptor
T0183	Pramiracetam	CI-879	Others
	Pramiracetam (CI-879), derived from piracetam, is a more effective nootropic drug . According to reports, Pramiracetam improved cognitive defects related with traumatic brain wounds. Pramiracetam was also potent in the t...		Others
T8787	Drotaverine hydrochloride		PDE
	Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor，and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally rela...		PDE
T1623	Lopinavir	ABT-378	SARS-CoV , HIV Protease
	Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related dr...		SARS-CoV , HIV Protease
T21629	Loxapine		Dopamine Receptor , 5-HT Receptor
	Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ...		Dopamine Receptor , 5-HT Receptor
T8873	Bractoppin		Others , DNA/RNA Synthesis
	Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...		Others , DNA/RNA Synthesis
T3S1471	Cucurbitacin IIA	Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA	Apoptosis , Survivin
	1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a ...		Apoptosis , Survivin
T0910	Terpin hydrate	Terpin Monohydrate,cis-Terpin hydrate	Others
	Terpin hydrate, a cis-form hydrate, is derived from sources such as oil of turpentine, oregano, thyme, and eucalyptus. It is used as an insect repellent and expectorant. Terpin hydrate(cis-Terpin hydrate) is commonly use...		Others
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T24958	(R)-Licarbazepine Acetate	BIA2-059,Licarbazepine acetate, (R)-,BIA 2-059,BIA-2-059
	(R)-Licarbazepine Acetate is a hopeful antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine.
T27171	Diethylhomospermine	DEHOP,BE-4-4-4,DEHSPM,DE-444
	Diethylhomospermine is a drug potentially for the treatment of AIDS-related chronic diarrhea.Diethylhomospermine also shows promising anticancer activity.
T31454	Difenamizole	Difenamizolum,BRN 0698538,Diphenamizole,Pasalin
	Difenamizole is a nonsteroidal anti-inflammatory drug (NSAID), which is a pyrazolinone analgesic drug-related to Analgin. It has monoaminergic properties, including inhibition of monoamine oxidase, an increase of pargyli...
T69814	Neramexane Free Base
	Neramexane Free Base is a drug related to memantine, which acts as an NMDA antagonist and has neuroprotective effects. It is being developed for various possible applications, including treatment of tinnitus, Alzheimer's...
T33978	Phenindamine Tartrate	Pernovine,Thephorin,Nolahist,Phenindamine,Plegine
	Phenindamine Tartrate is an antihistamine and anticholinergic drug closely related to cyproheptadine. It is used to treat symptoms of the common cold and allergies, such as sneezing, itching, rashes, and hives.