Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally related to papaverine
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 47.00 | |
10 mg | In stock | $ 72.00 | |
25 mg | In stock | $ 139.00 | |
50 mg | In stock | $ 263.00 | |
100 mg | In stock | $ 393.00 | |
500 mg | In stock | $ 939.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 52.00 |
Description | Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally related to papaverine |
In vitro | drotaverine not only relaxed the precontracted tracheal preparations but also decreased mediator-induced contraction.?These effects of drotaverine were concentration dependent, with a significantly higher potency on the KCl-induced response, than on either the histamine or methacholine induced one.?A similar result was noted for nifedipine.?The PDE inhibitor, theophylline, also relaxed the precontracted preparations but was ineffective on the mediator-induced contraction in a physiologically relevant concentration range. |
Molecular Weight | 433.968 |
Formula | C24H32ClNO4 |
CAS No. | 985-12-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (57.61 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Drotaverine hydrochloride 985-12-6 Metabolism PDE Ca2+ channels Inhibitor Ca channels inhibit Drotaverine Phosphodiesterase (PDE) Drotaverine Hydrochloride Calcium Channel inhibitor