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Diethylhomospermine

Catalog No. T27171 CAS 119422-08-1

Synonyms: DEHOP, BE-4-4-4, DEHSPM, DE-444

Diethylhomospermine is a drug potentially for the treatment of AIDS-related chronic diarrhea.Diethylhomospermine also shows promising anticancer activity.

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Diethylhomospermine, CAS 119422-08-1

Pack Size	Availability	Price/USD
25 mg	10-14 weeks	$ 3,320.00
50 mg	10-14 weeks	$ 4,380.00
100 mg	10-14 weeks	$ 6,100.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

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Description

Diethylhomospermine is a drug potentially for the treatment of AIDS-related chronic diarrhea.Diethylhomospermine also shows promising anticancer activity.

Synonyms	DEHOP, BE-4-4-4, DEHSPM, DE-444
Molecular Weight	286.5
Formula	C16H38N4
CAS No.	119422-08-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Bayes M, Rabasseda X, Prous JR. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2004 Sep;26(7):587-612. Review. PubMed PMID: 15538546. 2. Wilding G, King D, Tutsch K, Pomplun M, Feierabend C, Alberti D, Arzoomanian R. Phase I trial of the polyamine analog N1,N14-diethylhomospermine (DEHSPM) in patients with advanced solid tumors. Invest New Drugs. 2004 Apr;22(2):131-8. PubMed PMID: 14739661. 3. Bergeron RJ, Wiegand J, Fannin TL. Control of irritable bowel syndrome with polyamine analogs: a structure-activity study. Dig Dis Sci. 2001 Dec;46(12):2615-23. PubMed PMID: 11768250. 4. Bergeron RJ, Weimar WR, Müller R, Zimmerman CO, McCosar BH, Yao H, Smith RE. Effect of polyamine analogues on hypusine content in JURKAT T-cells. J Med Chem. 1998 Sep 24;41(20):3901-8. PubMed PMID: 9748365.

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Diethylhomospermine 119422-08-1 DEHOP BE-4-4-4 DEHSPM DE 444 DE444 DE-444 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.