disease — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN6715	7-Ketocholesterol		Others
	7-Ketocholesterol is a metabolite of Cholesterol		Others
T22251	680C91		Others
	680C91 is a potent and selective inhibitor of TDO, and its Ki is 51 nM.		Others
TN1355	Acanthoside B		Immunology/Inflammation related
	Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.		Immunology/Inflammation related
T20993	Memantine		Others
	Memantine, an amantadine derivative with some dopaminergic effects, has been proposed as an antiparkinson agent and has may be used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by ...		Others
T36596	Isoprothiolane		Antifungal
	Isoprothiolane is a foliar spray fungicide with eradicant and protectant activities against fungal diseases of rice plant caused by Pyvioutavia oryzae Cav.		Antifungal
T2548	Diflorasone		Glucocorticoid Receptor
	Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...		Glucocorticoid Receptor
TN1772	Isoastilbin		Anti-infection , Tyrosinase , Antibacterial
	Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an...		Anti-infection , Tyrosinase , Antibacterial
T9062	CA77.1		Autophagy
	CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD).		Autophagy
T3464	PHCCC	(-) PHCCC	GluR
	PHCCC ((-) PHCCC) is a Group I metabotropic glutamate receptor antagonist and a positive allosteric modulator of mGluR4. It also is a potent to antagonism for mGluR2 and mGluR8.		GluR
T1880	P7C3		Others
	The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, be...		Others
T1532	Pidotimod		Others , Antibacterial
	Pidotimod is a synthetic dipeptide with immunomodulatory properties.		Others , Antibacterial
T5S1923	Schisandrin C	Schizandrin-C,Wuweizisu-C	Apoptosis , Others , Virus Protease
	Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.		Apoptosis , Others , Virus Protease
TN1416	Ayanin		IL Receptor , P450 , PARP , PDE
	Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio...		IL Receptor , P450 , PARP , PDE
T3769	Tenuifolin		Others , Beta-Secretase , AChE
	Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.		Others , Beta-Secretase , AChE
T7626	Budipine		Others
	Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent.		Others
T21883	Gedunin		HSP
	Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation.		HSP
T2718	Palmatine chloride		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
	Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
T21687	Conoidin A		Parasite
	Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation ...		Parasite
T2S1720	Huperzine B		AChE
	1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.		AChE
T4473	Ibiglustat	Venglustat,SAR402671,GZ402671	Transferase
	Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthe...		Transferase