Home Tools
Log in
Cart

Search Result

Search Results for " anxiety "

20

Compounds

Cat No. Product Name Synonyms Targets
T20884 Hydroxyzine Hydroxyzine free base Histamine Receptor
Hydroxyzine (Hydroxyzine free base) is an antagonist of histamine H1-receptor.
T22994 ML 154 Neuropeptide Y Receptor
neuropeptide S receptor (NPSR) antagonist
T8318 BNC210 H-Ile-Trp-OH,IW-2143 AChR
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
T2200 Hydroxyzine dihydrochloride Hydroxyzine 2HCl Histamine Receptor
Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIR...
T1997 JNJ-31020028 JNJ 31020028 Neuropeptide Y Receptor
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
T7061 Duloxetine Serotonin Transporter
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.
T16421 P-MPPI hydrochloride 5-HT Receptor
p-MPPI hydrochloride is a selective antagonist of 5-HT1A receptor, and has antidepressant and anxiolytic-like effects.
T3183 SAX-187 WAY 181187,WAY181187 5-HT Receptor
SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.
T16472 Pericyazine Propericiazine,RP 8909 Dopamine Receptor
Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe anxiety states and psych...
T6043 PF-3845 FAAH , Autophagy
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
T9272 Xaliproden hydrochloride Dopamine Receptor , 5-HT Receptor
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.
T8004 SNAP 94847 hydrochloride GPR , Melanin-concentrating Hormone Receptor (MCHR)
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)
T2710 TCS 1102 OX Receptor
TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).
T7644 DPN Diarylpropionitrile Apoptosis , Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Autophagy
DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .
T21011 Buspirone Buspirone free base,Ansial 5-HT Receptor
Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.
T2067 NS11394 NS 11394 GABA Receptor
NS11394 is a effective and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of α(5) > α(3) > α(2) > α(1) at GABA(A) alpha subunit-containing receptors.
T2463 ML141 CID-2950007 Apoptosis , CDK , Ras
ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).
T7699 AZD7325 AZD-7325 P450 , GABA Receptor
AZD7325 (AZD-7325) is a GABA-Aα2,3 -selective receptor modulator.
TN2004 Obtusin MAO , Monoamine Oxidase
Obtusin is a natural product.
T21654 1-Oleoyl lysophosphatidic acid sodium 1-Oleoyl lysophosphatidic acid sodium salt LPA Receptor
1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2
1 2 3 4 5 6 7 8
TargetMol