antihypertensive — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T80661	Antihypertensive sulfonanilide XVII		Others
	Antihypertensive sulfonanilide XVII is an orally available antihypertensive sulfonanilide small molecule compound for the study of hypertension.		Others
T79267	Antihypertensive agent 3
	Antihypertensive agent 3 (compound 4a), an angiotensin II receptor 1 antagonist, demonstrates antihypertensive activity in spontaneously hypertensive rats (SHRs) [1].
T79266	Antihypertensive agent 2
	Antihypertensive agent 2 (Compound 4g) exhibits effective antagonistic activities against angiotensin II receptor 1 and reduces blood pressure with equal or greater potency than Losartan [1].
T5471	GUANABENZ		Adrenergic Receptor
	GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist.		Adrenergic Receptor
T21640	Talinolol		Adrenergic Receptor
	(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.		Adrenergic Receptor
T8270	Deserpidine	Harmonyl	RAAS
	Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive propertie...		RAAS
TN1733	Hesperetin 7-O-glucoside		Anti-infection , Antibacterial , HMG-CoA Reductase
	Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inh...		Anti-infection , Antibacterial , HMG-CoA Reductase
T2519	Lercanidipine	Masnidipine	Calcium Channel
	Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class.		Calcium Channel
T0300	Pargyline	Pargylamine,Paragyline	MAO , Monoamine Oxidase
	Pargyline (Pargylamine) is a monoamine oxidase inhibitor with antihypertensive properties.		MAO , Monoamine Oxidase
T0114	Trichlormethiazide	Naqua,Metahydrin,Trichlormetazid	ATPase , Carbonic Anhydrase
	Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and ...		ATPase , Carbonic Anhydrase
TN1644	Flavanomarein		Others
	Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...		Others
T6641	Rilmenidine Phosphate		Apoptosis , Adrenergic Receptor , Autophagy , Imidazoline Receptor
	Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.
T21957	Guanabenz hydrochloride	NE56490	Adrenergic Receptor
	Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects.		Adrenergic Receptor
T0388	Cilnidipine	FRC-8653	Calcium Channel
	Cilnidipine (FRC-8653)(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.		Calcium Channel
T2531	Eprosartan Mesylate	SKF-108566J	RAAS
	Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.		RAAS
T7656	Apelin-13
	Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ...
T19654	Guanoclor	VATENSOL	Others
	Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.		Others
T6086	Clopamide	Brinaldix,Adurix,Aquex	Sodium Channel
	Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.		Sodium Channel
T1578	Pargyline hydrochloride	Pargylamine hydrochloride	MAO , Monoamine Oxidase
	Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.		MAO , Monoamine Oxidase
T2939	Forskolin	Coleonol,Colforsin	FXR , Adenylyl cyclase , AChR , Autophagy
	Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the...		FXR , Adenylyl cyclase , AChR , Autophagy