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Clopamide

Catalog No. T6086 CAS 636-54-4

Synonyms: Brinaldix, Adurix, Aquex

Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.

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Clopamide, CAS 636-54-4

Pack Size	Availability	Price/USD
50 mg	In stock	$ 41.00
100 mg	In stock	$ 66.00
200 mg	In stock	$ 94.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.

Synonyms	Brinaldix, Adurix, Aquex
Molecular Weight	345.84
Formula	C14H20ClN3O3S
CAS No.	636-54-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (72.29 mM)

References and Literature

1. du Preez MJ, Lockett CJ. J Am Coll Nutr. 1991 Feb;10(1):34-7. 2. McNeil JJ, et al. Clin Pharmacol Ther. 1987 Sep;42(3):299-304.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Membrane Protein-targeted Compound Library Anti-Cancer Compound Library FDA-Approved & Pharmacopeia Drug Library Bioactive Compound Library Orally Active Compound Library Bioactive Compounds Library Max ReFRAME Related Library Ion Channel Inhibitor Library Human Metabolite Library

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Clopamide 636-54-4 Membrane transporter/Ion channel Sodium Channel cardiac diuretic Na+ channels Na channels inhibit thiazide-like antihypertensive Brinaldix Adurix Aquex SLC12A3 Inhibitor failure inhibitor

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