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Trichlormethiazide

Catalog No. T0114 CAS 133-67-5

Synonyms: Naqua, Metahydrin, Trichlormetazid

Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.

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Trichlormethiazide, CAS 133-67-5

Pack Size	Availability	Price/USD
500 mg	In stock	$ 45.00
1 g	In stock	$ 53.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.54%

Purity: 99.32%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Naqua, Metahydrin, Trichlormetazid
Molecular Weight	380.66
Formula	C8H8Cl3N3O4S2
CAS No.	133-67-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (131.4 mM)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

References and Literature

1. Temperini C, et al. Bioorg Med Chem. 2009 Feb 1;17(3):1214-21.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Drug Repurposing Compound Library Membrane Protein-targeted Compound Library Anti-Hypertension Compound Library Ion Channel Inhibitor Library FDA-Approved Drug Library Mitochondria-Targeted Compound Library NO PAINS Compound Library Anti-Metabolism Disease Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Trichlormethiazide 133-67-5 Membrane transporter/Ion channel Metabolism ATPase Carbonic Anhydrase Naqua hypertension diuretic antihypertensive Inhibitor Metahydrin acute renal failures inhibit Trichlormetazid angiotensin inhibitor

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