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Eprosartan Mesylate

Eprosartan Mesylate
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Eprosartan Mesylate

Catalog No. T2531Cas No. 144143-96-4
Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.
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Pack SizePriceAvailabilityQuantity
10 mg$40In Stock
25 mg$63In Stock
50 mg$77In Stock
100 mg$112In Stock
200 mg$173In Stock
500 mg$292In Stock
1 mL x 10 mM (in DMSO)$40In Stock
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Product Introduction

Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.
In vitro
In a study involving brain and spinal cord injured rats, Eprosartan (0.3 mg/kg i.v.) was observed to induce a hypertensive response following spinal cord stimulation.
In vivo
Eprosartan effectively inhibits [125I]-Angiotensin II in human tissues (adrenal cortex, liver, cloned AT1 receptors) with an IC50 range of 1.4-3.9 nM and in rat tissues (mesenteric artery, adrenal cortex, glomeruli) with an IC50 range of 1.5-9.2 nM. In isolated perfused proximal tubules of rabbits, Eprosartan (100 nM) completely blocks the isosmotic fluid absorption induced by Angiotensin II.
Chemical Properties
Molecular Weight520.62
Cas No.144143-96-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: 4 mg/mL (7.68 mM)
DMSO: 104 mg/mL (199.76 mM)
Solution Preparation Table
1 mM1.9208 mL9.6039 mL19.2079 mL96.0393 mL
5 mM0.3842 mL1.9208 mL3.8416 mL19.2079 mL
10 mM0.1921 mL0.9604 mL1.9208 mL9.6039 mL
20 mM0.0960 mL0.4802 mL0.9604 mL4.8020 mL
50 mM0.0384 mL0.1921 mL0.3842 mL1.9208 mL
100 mM0.0192 mL0.0960 mL0.1921 mL0.9604 mL


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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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