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Guanoclor

Catalog No. T19654 CAS 5001-32-1

Synonyms: VATENSOL

Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.

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Guanoclor, CAS 5001-32-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 37.00
2 mg	In stock	$ 50.00
5 mg	In stock	$ 68.00
10 mg	In stock	$ 98.00
25 mg	In stock	$ 178.00
50 mg	In stock	$ 255.00
1 mL * 10 mM (in DMSO)	In stock	$ 74.00

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Purity: 99.37%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.

Synonyms	VATENSOL
Molecular Weight	263.12
Formula	C9H12Cl2N4O
CAS No.	5001-32-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 2.63 mg/ml (10 mM), Sonication is recommended.

References and Literature

1. SINNIAH R, GATENBY PB. CLINICOPHARMACOLOGICAL ASSESSMENT OF THE NEW ANTI-HYPERTENSIVE COMPOUND GUANOCLOR (VATENSOL). Ir J Med Sci. 1965 Mar;471:111-24. PubMed PMID: 14295356. 2. BENDER S. TO-DAY'S DRUGS. GUANOCLOR. Br Med J. 1964 Jul 25;2(5403):238-9. PubMed PMID: 14150915; PubMed Central PMCID: PMC1817852. 3. Mackinnon J, el-Baz LM. A comparison of guanoclor and methyldopa in the treatment of severe hypertension. Br J Clin Pract. 1971 Mar;25(3):135-7. PubMed PMID: 4929159. 4. Mehta AB, Biswas AK, Pinto IJ, Sheth UK. Clinical assessment of the new antihypertensive Compound--1029 (Vatensol)--Guanoclor. Indian Heart J. 1967 Oct;19(4):322-8. PubMed PMID: 4870898.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library NO PAINS Compound Library ReFRAME Related Library Bioactive Compounds Library Max

Dose Conversion

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Guanoclor 5001-32-1 Others Dopamine beta-hydroxylase Dopamine β-hydroxylase Inhibitor noradrenaline synthesis adrenergic neurone-blocking agent Dopamine β-monooxygenase antihypertensive Dopamine beta-monooxygenase inhibit VATENSOL inhibitor

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