a-casein — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14069	A-3 hydrochloride		CaMK , Casein Kinase , PKA , PKC
	A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectiv...		CaMK , Casein Kinase , PKA , PKC
T8987	Epiblastin A		Casein Kinase
	Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).		Casein Kinase
TP1695	α-Casein (90-95)	α-Casein 90-95
	α-Casein (90-95) is a peptide fragment of α-Casein.
T39482	Casein Kinase inhibitor A86	Casein Kinase inhibitor A86
	Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α). Additionally, it displays inhibitory actions towards CDK7 (TFIIH) and CDK9 (P-TEFb). Furthermore, Casein Kin...
T77708	Casein kinase 1δ-IN-7		Casein Kinase
	Casein kinase 1δ-IN-7 is a Casein kinase 1δ inhibitor for neurodegenerative diseases such as Alzheimer's disease.		Casein Kinase
T64350	Casein kinase 1δ-IN-3		Casein Kinase
	Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.		Casein Kinase
T2449	D4476	D 4476,Casein Kinase I Inhibitor	Apoptosis , Casein Kinase , ALK , Autophagy
	D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).		Apoptosis , Casein Kinase , ALK , Autophagy
T21915	TBCA	Casein Kinase II Inhibitor III, TBCA	Casein Kinase
	TBCA (Casein Kinase II Inhibitor III, TBCA) is a highly selective CK2 (casein kinase II) inhibitor, IC50 = 110 nM, Ki = 77 nM. TBCA shows selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases.		Casein Kinase
T64376	Casein kinase 1δ-IN-9		NADPH
	Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.		NADPH
T7390	DMAT	Casein kinase II Inhibitor,CK2 Inhibitor	Casein Kinase
	DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).		Casein Kinase
T80725	ZK53		Others
	ZK53 is a selective and potent activator of mitochondrial casein hydrolase protease P (HsClpP).ZK53 induces apoptosis and inhibits the hydrolysis of alpha-casein by HsClpP.ZK53 inhibits tumour growth in xenografts and na...		Others
T83969	Casein		Hydroxylase
	Casein is a milk protein with multiple roles in a novel drug delivery system that affects postprandial amino acid delivery in different ways through its intragastric coagulation properties.		Hydroxylase
T2259	Silmitasertib	CX-4945	Casein Kinase , Autophagy
	Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).		Casein Kinase , Autophagy
T77500	Casein kinase 1δ-IN-6		Casein Kinase
	Casein kinase 1δ-IN-6 is a potent and selective inhibitor of the protein kinase CK-1δ with an IC50 of 23 nM.Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays.C...		Casein Kinase
T5056	PF-4800567		Casein Kinase
	PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.		Casein Kinase
T2695	TBB	Casein Kinase II Inhibitor I,NSC 231634,4,5,6,7-tetrabromobenzotriazole	GSK-3 , Casein Kinase , CDK
	TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).		GSK-3 , Casein Kinase , CDK
T5393	CK1-IN-1	PUN51207	p38 MAPK , Casein Kinase
	CK1-IN-1 (PUN51207) is a casein kinase 1 (CK1) inhibitor. CK1-IN-1 has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively.		p38 MAPK , Casein Kinase
T1828	TTP 22		Casein Kinase
	TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM, and shows selectivity >250-fold for CK2 over JNK3, ROCK1, and MET(IC50> 10 uM).		Casein Kinase
T19913	CKI-7	CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl	ROCK , SGK , Casein Kinase , CDK , S6 Kinase
	CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.		ROCK , SGK , Casein Kinase , CDK , S6 Kinase
T15572	IN-1130		ALK
	IN-1130 is a selective inhibitor of ALK5 with IC50 values of 5.3 nM, 36 nM, and 4.3 μM for phosphorylation of ALK5-mediated Smad3, ALK5 phosphorylation of casein and p38α mitogen-activated protein kinase.		ALK