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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9031 | MCU-i4 | Others , Mitochondrial Metabolism | |
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth. | |||
T23101 | O-3M3FBS | Others | |
Inactive analog of m-3M3FBS (PLC activator) | |||
T6856 | Halofuginone | Tempostatin,empostatin,RU-19110 | Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal. | |||
T3524 | Halofuginone hydrobromide | Tempostatin,RU-19110 (hydrobromide),Stenorol | Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce... | |||
TP1911L | CALP3 acetate(261969-05-5 free base) | Calcium Channel | |
CALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels ... | |||
T12201 | Nebracetam hydrochloride | WEB 1881 FU hydrochloride | AChR |
Nebracetam hydrochloride (WEB 1881 FU hydrochloride) is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 m... | |||
TP1179L | Porcine dynorphin A(1-13) acetate | Dynorphin A Porcine Fragment 1-13 acetate,Porcine dynorphin A(1-13) acetate(72957-38-1 free base) | Opioid Receptor |
Porcine dynorphin A(1-13) acetate (Dynorphin A Porcine Fragment 1-13 acetate) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) cause... | |||
TN2322 | Yangambin | Calcium Channel , PAFR | |
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti... | |||
T5S0527 | Rhodojaponin III | Others | |
1. Rhodojaponin III has antifeedant and oviposition deterrence effects against many kinds of insects, BdorCSP2 of B. dorsalis could be involved in chemoreception of Rhodojaponin III and played a critical role. 2. Rhodoja... | |||
T5S1632 | Barlerin | 8-O-Acetylshanzhiside methyl ester,ND01 | VEGFR , TNF , NF-κB , Akt , Caspase |
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e... | |||
T6S1418 | Praeruptorin C | Antioxidant , Calcium Channel | |
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ... | |||
T1407 | (-)-Menthol | L-Menthol,Levomenthol,Menthomenthol,Menthacamphor | Opioid Receptor , Endogenous Metabolite , TRP/TRPV Channel |
(-)-Menthol (Levomenthol) is a levo isomer of menthol, an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties. When added to pharmaceuticals and foo... | |||
TP2170 | CALP3 TFA(261969-05-5 free base) | CALP3 TFA | Calcium Channel |
CALP3 TFA is a potent Ca2+ channel blocker that activates EF-hand motifs of Ca2+-binding proteins. It can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin, Ca2+ channels, and pumps. | |||
T75789 | CALP3 TFA | ||
CALP3 TFA, a Ca2+-like peptide and potent Ca2+ channel blocker, activates EF hand motifs in Ca2+-binding proteins. It can mimic increased [Ca2+]i, modulating the activity of Calmodulin (CaM), Ca2+ channels, and pumps. Th... | |||
T7009 | Soyacerebroside II | IL Receptor , Calcium Channel | |
Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral... | |||
T75928 | Des-Gln14-Ghrelin TFA | ||
Des-Gln14-Ghrelin TFA serves as a potent endogenous ligand for the growth hormone secretagogue receptor, effectively inducing increases in intracellular calcium levels ([Ca2+]i) in CHO-GHSR62 cells with an EC50 of 2.4 nM... | |||
T13904 | 18:0 LYSO-PE | Stearoyl lysophosphatidylethanolamine | Others |
18:0 LYSO-PE is a compound that induces an increase in [Ca2+]i. 18:0 LYSO-PE can be used as a phospholipid (PL) standard for lipid analysis by electrospray mass spectrometry (ESI-MS)/MS. | |||
TN2169 | Saikogenin D | IL Receptor , Calcium Channel , Prostaglandin Receptor | |
Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of [Ca2+]i that is attributed to Ca2+ release from intracellu... | |||
T69357 | AL-34662 | ||
AL-34662 is a serotonin-2 receptor agonist with antihypertensive action. AL-34662 has a high-affinity for the 5-HT2 receptor and may potentially lead mobilization of [Ca2+]i in h-CM and h-TM cells leading to a decrease ... | |||
TP1532 | γ-2-MSH (41-58), amide | ||
Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cel... |