keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 137.00 | |
5 mg | In stock | $ 556.00 | |
10 mg | In stock | $ 783.00 | |
25 mg | In stock | $ 1,220.00 | |
50 mg | In stock | $ 1,650.00 | |
100 mg | In stock | $ 2,230.00 |
Description | CALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. |
In vitro | CALP3 inhibits glutamate caused a large sustained increase in [Ca2+]i in a dose-dependent manner (IC50=37.25 μM) in Fura-2-loaded neuronal cultures. CALP3 inhibits glutamate-induced cytotoxicity in a dose-dependent manner (IC50=50.97 μM) in cultured rat neocortical neurons. CALP3 causes dose-dependent inhibition of apoptosis (IC50=33.41 μM). CALP3 (100 μM) inhibits apoptosis induced by HIV gp120 and SAg in Human T cells. CALP3 (100?μM; 15?min pretreatment) reduces gossypol-induced necrosis and increases the fraction of live cells[1][2]. |
Molecular Weight | 941.12 |
Formula | C46H72N10O11 |
CAS No. | TP1911L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CALP3 acetate(261969-05-5 free base) TP1911L Membrane transporter/Ion channel Metabolism Calcium Channel CALP-3 acetate(261969-05-5 free base) CALP3 acetate(261969055 free base) CALP3 acetate(261969 05 5 free base) inhibitor inhibit