uva — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0473	Arbutin	Uva,p-Arbutin,p-Arbutin,β-Arbutin	Tyrosinase
	Arbutin (p-Arbutin)(β-Arbutin) is a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos and can inhibit tyrosinase and thus prevent the formation of melanin.		Tyrosinase
T9048	Ecamsule		Others
	Ecamsule is a benzylidene camphor derivative, many of which are known for their excellent photostability. It can be added to many sunscreens to filter out UVA rays.		Others
T19310	Ensulizole	2-PHENYLBENZIMIDAZOLE-5-SULFONIC ACID,2-Phenyl-1H-benzo[d]imidazole-5-sulfonic acid,Phenylbenzimidazole sulfonic acid	Others
	Ensulizole (2-PHENYLBENZIMIDAZOLE-5-SULFONIC ACID) can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation. Ensulizole is a water soluble sunscreen ingredient.Ensulizole...		Others
T7769	Nonapeptide-1	Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-,Melanostatine™ 5	Others
	Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.		Others
T21405	Fluvastatin	Canef,XU-62320,Vastin,Cranoc,Lescol	HMG-CoA Reductase
	Fluvastatin (XU-62320) is a potent and competitive HMG-CoA reductase inhibitor (IC50: 8 nM) that inhibits oxidative stress in vascular smooth muscle cells through an Nrf2-dependent pathway, and is used for the reduction ...		HMG-CoA Reductase
T2516	Amuvatinib	MP470,HPK 56	Apoptosis , FLT , c-Met/HGFR , c-RET , DNA/RNA Synthesis , PDGFR , c-Kit
	Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.
T8030	Ethyl pyruvate		Apoptosis , Antioxidant
	Ethyl pyruvate is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions.		Apoptosis , Antioxidant
T38863	Luvadaxistat	TAK-831,Luvadaxistat
	TAK-831 is a potent and highly selective inhibitor of D-amino acid oxidase (DAAO), offering great potential for utilization in schizophrenia research.
T12652	(Rac)-5-Keto Fluvastatin	5-Ketofluvastatin,3-Hydroxy-5-Keto Fluvastatin,rac 5-Keto Fluvastatin	Others
	(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.		Others
T1487	Fluvastatin sodium	XU 62320 sodium,XU-62-320,Fluvastatin sodium salt	Ferroptosis , HMG-CoA Reductase , Autophagy
	Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.		Ferroptosis , HMG-CoA Reductase , Autophagy
T11684	Isoguvacine hydrochloride	1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride	GABA Receptor
	Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synaptic cortical membranes and activates α1β2γ2S, α2β2γ2S, α3β2γ2...		GABA Receptor
T5805	Guvacoline hydrochloride	Norarecoline hydrochloride	AChR
	Guvacoline hydrochloride (Norarecoline hydrochloride) is a muscarinic agonist.		AChR
T7557	Guvacine hydrochloride		GABA Receptor
	Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)		GABA Receptor
T68018	Tuvatexib		VDAC
	Tuvatexib is a small molecule VDAC/HK2 dual modulator.		VDAC
T1510	Rosuvastatin calcium	ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.		Potassium Channel , HMG-CoA Reductase , Autophagy
T77695	Muvalaplin	LY3473329	Others
	Muvalaplin (LY3473329) is an orally active lipoprotein (a) Lp(a) reagent that inhibits Lp(a) formation by blocking apo(a)-apo B100 interactions.		Others
T4891	Sodium phenylpyruvate	Phenylpyruvic acid, sodium salt	Others
	Sodium phenylpyruvate (Phenylpyruvic acid, sodium salt) is a substrate for phenylpyruvate decarboxylase and phenylpyruvate tautomerase.		Others
TN2290	Uvaol		Endogenous Metabolite , JNK , PPAR
	Uvaol is present in olives and virgin olive oil with anti-inflammatory, anti-proliferative, and vasorelaxant activities.		Endogenous Metabolite , JNK , PPAR
T1676	Rosuvastatin	ZD 4522	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting...		Potassium Channel , HMG-CoA Reductase , Autophagy
T61154	Colistin adjuvant-2
	Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].