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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35593 | Semapimod tetrahydrochloride | CPSI-2364 tetrahydrochloride | TLR , MAPK |
Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a synthetic ornithine mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor that interferes with macrophage and microgl... | |||
T2064 | Semaxinib | SU5416 | VEGFR |
Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR than PDGFRβ, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the... | |||
T2496 | (Z)-Semaxinib | SU5416 | VEGFR |
(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative w... | |||
T3574 | Sematilide hydrochloride | CK-1752A,CK-1752,Sematilide HCl | Potassium Channel |
Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the ... | |||
T19850 | Semaglutide | Glucagon Receptor | |
Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor). | |||
T19850L | Semaglutide Acetate | Semaglutide Acetate(910463-68-2 Free base) | Glucagon Receptor |
Semaglutide Acetate is an agonist of a glucagon-like peptide 1 (GLP-1) receptor and can be used in studies about the treatment of type 2 diabetes. | |||
T6125 | Semagacestat | LY450139 | Beta Amyloid , Gamma-secretase |
Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM). | |||
T21268L | Semax acetate(80714-61-0 free base) | Others | |
Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties. | |||
T34610 | Semapimod hydrochloride dihydrate | ||
Semapimod hydrochloride dihydrate is a biochemical. | |||
T21268 | Semax | ||
Semax is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties. | |||
T125571 | Eriosematin A | ||
Eriosematin A is a useful organic compound for research related to life sciences and the catalog number is T125571. | |||
T79304 | Semapimod | CPSI-2364,CNI-1493 free base | |
Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6. It hinders TLR4 signaling with an IC50 of approximately 0.3 μM, impedes p38 MAPK, and reduces nitric oxide ... | |||
T81180 | Semastatin-5B | ||
Semastatin-5B, an anti-angiogenic peptide composed of 17 amino acids, can be derived from proteins featuring type I thrombospondin motifs [1]. | |||
T34610L | Semapimod mesylate | Semapimod tetramesylate | |
Semapimod mesylate is a biochemical. | |||
T12879 | Sematilide | CK-1752 | Others |
Sematilide is a blocker of selective IKr channel. | |||
T12878 | Semaglutide TFA (910463-68-2 free base) | Semaglutide TFA | Glucagon Receptor |
Semaglutide TFA is a agonist of glucagon-like peptide-1 (GLP-1) receptor,with a potential for type 2 diabetes treatment. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11223 | Eriosematin | Others | |
Eriosematin has anti-proliferative and apoptosis-inducing properties and is a compound extracted from the root of Flemingia philippinensis in the Philippines. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01906 | SEMA4D Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SEMA4D Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80.7 kDa and the accession number is AAH54500.1. | |||
TMPY-04625 | SEMA3A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SEMA3A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.6 kDa and the accession number is A0A803Z7F8. | |||
TMPY-00124 | SEMA3A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SEMA3A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.7 kDa and the accession number is Q14563. | |||
TMPK-01216 | SEMA7A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SEMA7A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is Q9QUR8. | |||
TMPJ-01176 | SEMA4C Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. P... | |||
TMPJ-00395 | SEMA4D Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
SEMA4D is a member of the semaphorin family,contains one Ig-like C2-type domain, one PSI domain and one Sema domain. SEMA4D is strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous t... | |||
TMPJ-00383 | SEMA3A Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can f... | |||
TMPY-01843 | SEMA6A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SE... | |||
TMPK-00741 | SEMA7A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SEMA7A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is O75326-1. | |||
TMPY-05780 | SEMA4D Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SEMA4D Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 105.95 kDa and the accession number is AAH54500.1. | |||
TMPJ-01293 | SEMA3C Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Semaphorin 3C is one of six Class 3 secreted semaphorins, which are potent chemorepellents, that play a role in axon and/or vascular guidance during development can be up-regulated in the process of tumor progression. Se... | |||
TMPJ-01169 | SEMA4A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Semaphorin-4A (SEMA4A) belongs to the semaphorin family which contains a Ig-like C2-type domain, a PSI domain and a Sema domain. SEMA4A is expressed from day 10 in the embryo, and low levels are found between days 10-12.... | |||
TMPY-02360 | SEMA3A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
SEMA3A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.7 kDa and the accession number is O08665. | |||
TMPK-00404 | SEMA4D Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, ... | |||
TMPK-01379 | SEMA4D Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, ... | |||
TMPK-00403 | SEMA4D Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, ... | |||
TMPJ-01349 | SEMA4B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domai... | |||
TMPJ-01355 | SEMA4G Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Semaphorin-4G is belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a sem... | |||
TMPJ-01348 | SEMA4B Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B ... | |||
TMPJ-00396 | SEMA4D Protein, Human, Recombinant (aa 22-734, His) | Human | HEK293 Cells |
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB... | |||
TMPY-03164 | SEMA4D Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
SEMA4D Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 103.4 kDa and the accession number is A0A8I6G5Q1. | |||
TMPY-02006 | SEMA4A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SEMA4A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 99 kDa and the accession number is Q9H3S1-1. | |||
TMPY-01857 | SEMA4A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SEMA4A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.4 kDa and the accession number is Q9H3S1-1. | |||
TMPH-02446 | SEMA4D Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
SEMA4D Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 81.9 kDa and the accession number is H9FNS0. | |||
TMPY-01836 | SEMA4D Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SEMA4D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80.2 kDa and the accession number is O09126. | |||
TMPY-00532 | SEMA4D Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 Cells |
SEMA4D Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80.7 kDa and the accession number is A0A8J8Y3Y5. | |||
TMPH-03369 | SEMA3A Protein, Rat, Recombinant (His) | Rat | E. coli |
May be involved in guiding growing axons towards their targets by forming a molecular boundary that instructs axons to engage in the formation of specific nerve tracts. Binds to neuropilin. Involved in the development of... | |||
TMPK-01034 | SEMA4B Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling p... | |||
TMPY-01570 | SEMA5A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SEMA5A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is Q13591. | |||
TMPH-02076 | Semaphorin-3F/SEMA3F Protein, Human, Recombinant (His & Myc) | Human | HEK293 Cells |
Semaphorin-3F/SEMA3F Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPH-02075 | Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-02074 | Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His) | Human | E. coli |
Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-03152 | SEMA5A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SEMA5A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is Q3UPZ0. | |||
TMPH-02077 | Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc) | Human | HEK293 Cells |
Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPY-03095 | SEMA4D Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
SEMA4D Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.8 kDa and the accession number is A0A8I6G5Q1. | |||
TMPY-02187 | SEMA5A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SEMA5A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.7 kDa and the accession number is Q13591. | |||
TMPJ-00415 | HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated | Human | HEK293 Cells |
Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which un... |